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22236 Amphetamines, Urine

Amphetamines, Urine
Test Code: AMP
Synonyms/Keywords
Amphetamine, Methamphetamine, MDMA, Ecstasy, MDA, Adderall, Speed, Phentermine, Ephedrine, Pseudoephedrine, Desoxyn, Crystal Meth, methylenedioxymethamphetamine, methylenedioxyamphetamine​, amines
Useful For
Detecting exposure to amphetamines to monitor compliance in taking prescribed medication or to detect abuse​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Urine​ Sage urine collection container​ Sterile plastic container with no preservatives​ 5 mL​ 3 mL​ 1.5 mL​
Specimen Stability Information
Specimen Type Temperature Time
Urine​ ​ Ambient​ 72 hours​
Refrigerate (Preferred)​ 30 days​
Frozen​ 30 days​
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​
If no confirmatory work is required: 1 day​
 
If confirmatory work is required: 4 days
 Beckman AU680 Clinical Chemistry System with Emit immunoassay and Liquid Chromatography/Tandem Mass Spectrometry (LCMS/MS) (if needed for confirmation)​
Test Information
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.
 
This test is a screen for the Amphetamines drug group by immunoassay; if the screen is positive, this test automatically includes LCMS/MS confirmation for the amphetamines drug group. Quantitation/confirmation charged separately if needed.  It is intended for use only in patients where an initial drug screening test has not already been performed (i.e. Point-of-Care drug screening cup, dipstick, etc.). The test will detect the presence of amphetamine, phentermine, methamphetamine, ephedrine, pseudoephedrine, MDA (methylenedioxyamphetamine), MDEA and MDMA (Ecstasy or methylenedioxymethamphetamine).
 
The Amphetamine drug group includes a variety of drugs of abuse, diet aids, and vasoconstrictor/decongestants found in OTC cold preparations.
Reference Range Information
Performing Location Reference Range
Marshfield​

Negative.  Positives are reported with a quantitative LCMS/MS result (phentermine, ephedrine and pseudoephedrine are reported with a qualitative LCMS/MS result).

Interpretation
Methamphetamine metabolizes to amphetamine, therefore both can be present after use of methamphetamine.
 
The street drug "Ecstasy" is MDMA (methylenedioxymethamphetamine).  MDMA metabolizes to MDA (methylenedioxyamphetamine), therefore both MDMA and MDA can be present after use of Ecstasy.
 
The approximate detection time of amphetamines in urine is between 1-3 days after last use.​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
80307​ ​ 1​ Single drug class​ ​
80326 ​ 1​ Amphetamine​ confirmation by LCMS/MS, 5 or more If needed​
G0480 ​ ​1 ​Amphetamines/Metamphetamine Confirmation by LCMS/MS ​For Medicare/Medicaid (if needed)
80359 ​ ​1 ​Methylenedioxyamphetamines (MDA, MDMA) ​If needed
Classification
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.
Synonyms/Keywords
Amphetamine, Methamphetamine, MDMA, Ecstasy, MDA, Adderall, Speed, Phentermine, Ephedrine, Pseudoephedrine, Desoxyn, Crystal Meth, methylenedioxymethamphetamine, methylenedioxyamphetamine​, amines
Ordering Applications
Ordering Application Description
​COM ​Amphetamine, Urine
​​Cerner​Amphetamine, Urine
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Urine​ Sage urine collection container​ Sterile plastic container with no preservatives​ 5 mL​ 3 mL​ 1.5 mL​
Specimen Stability Information
Specimen Type Temperature Time
Urine​ ​ Ambient​ 72 hours​
Refrigerate (Preferred)​ 30 days​
Frozen​ 30 days​
Useful For
Detecting exposure to amphetamines to monitor compliance in taking prescribed medication or to detect abuse​
Reference Range Information
Performing Location Reference Range
Marshfield​

Negative.  Positives are reported with a quantitative LCMS/MS result (phentermine, ephedrine and pseudoephedrine are reported with a qualitative LCMS/MS result).

Interpretation
Methamphetamine metabolizes to amphetamine, therefore both can be present after use of methamphetamine.
 
The street drug "Ecstasy" is MDMA (methylenedioxymethamphetamine).  MDMA metabolizes to MDA (methylenedioxyamphetamine), therefore both MDMA and MDA can be present after use of Ecstasy.
 
The approximate detection time of amphetamines in urine is between 1-3 days after last use.​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​
If no confirmatory work is required: 1 day​
 
If confirmatory work is required: 4 days
 Beckman AU680 Clinical Chemistry System with Emit immunoassay and Liquid Chromatography/Tandem Mass Spectrometry (LCMS/MS) (if needed for confirmation)​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
80307​ ​ 1​ Single drug class​ ​
80326 ​ 1​ Amphetamine​ confirmation by LCMS/MS, 5 or more If needed​
G0480 ​ ​1 ​Amphetamines/Metamphetamine Confirmation by LCMS/MS ​For Medicare/Medicaid (if needed)
80359 ​ ​1 ​Methylenedioxyamphetamines (MDA, MDMA) ​If needed
Classification
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.
For most current information refer to the Marshfield Laboratory online reference manual.