Other Amies medium based swab
0.5 mL fluid, 0.5 g tissue, or 1 swab
A definitive diagnosis of gonorrhea depends on the detection of its causative agent, Neisseria gonorrhoeae, by culture or PCR. However, Gram-negative diplococci contained within leukocytes in a urethral exudate from a male patient may be considered presumptive evidence of gonorrhea. Gram stain of other sources including cervical, throat, or rectal specimens should not be performed for gonorrhea since morphologically similar intracellular organisms are often found in these types of specimens. Urethral swabs from a male patient are used to prepare a smear at bedside. The slide should be labeled, allowed to air-dry and sent to the lab along with a swab specimen for gonorrhea culture. Alternately, two swabs can be submitted in bacterial transport medium and sent to the lab, where the smear will be prepared by laboratory personnel. Gram stain and gonorrhea culture should be ordered.