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23005 PSA, Total

PSA, Total
Test Code: PSA
Synonyms/Keywords
Prostate Specific Antigen, Total​
Specimen Requirements
 
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum or Plasma​Serum Separator Tube (SST)Red Top Tube (RTT), ​ Lithium-heparin Plasma Separator Tube (PST)​0.5 mL​0.4 mL​0.3 mL​
Collection Processing Instructions

Remove from cells within 2 hours of centrifugation.

​High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay. It is recommended that patients refrain from consuming any multivitamin or supplement containing biotin for at least 72 hours prior to collection of a blood sample.

Specimen Stability Information
Specimen Type Temperature Time
Serum/Plasma​ Ambient​ 8 hours​
Refrigerated​ 48 hours​
Frozen​ >48 hours​
Interference

Human Anti-Murine Antibodies (HAMA) may develop leading to test interference in patients receiving murine-based agents for chemotherapy or tumor-imaging studies.​

High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay.
Performing Laboratory Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Weston
 ​Monday through Sunday​ ​Less than 2 hours​ ​One Step Sandwich Enzyme Immunoassay/Siemens Dimension
​Neillsville​Monday through Sunday​​​Less than 2 hours​​​One Step Sandwich Enzyme Immunoassay/Siemens Dimension​
Reference Range Information
Performing Location Reference Range
All Performing Sites Males < = 49 years: 0.0 - 2.5 ng/mL
Males 50-59 years: 0.0 - 3.5 ng/mL
Males >= 60 years: 0.0 - 4.0 ng/mL​
Interpretation
Marshfield campus PSA assay shows improved sensitivity with a lower limit of detection of <0.03 ng/mL. Results in the range of 0-2 will be reported to two decimal places enabling improved monitoring of post-prostectomy patients.​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
84153 ​ ​ ​ ​ ​
Synonyms/Keywords
Prostate Specific Antigen, Total​
Ordering Applications
Ordering Application Description
​Centricity ​Prostate Specific Ag.
​Cerner ​Prostate Specific Antigen
​COM ​PSA, Total
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
 
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum or Plasma​Serum Separator Tube (SST)Red Top Tube (RTT), ​ Lithium-heparin Plasma Separator Tube (PST)​0.5 mL​0.4 mL​0.3 mL​
Collection Processing

Remove from cells within 2 hours of centrifugation.

​High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay. It is recommended that patients refrain from consuming any multivitamin or supplement containing biotin for at least 72 hours prior to collection of a blood sample.

Specimen Stability Information
Specimen Type Temperature Time
Serum/Plasma​ Ambient​ 8 hours​
Refrigerated​ 48 hours​
Frozen​ >48 hours​
Interference

Human Anti-Murine Antibodies (HAMA) may develop leading to test interference in patients receiving murine-based agents for chemotherapy or tumor-imaging studies.​

High doses of exogenous biotin (also termed Vitamin B7, Vitamin H or Coenzyme R) may interfere with this assay.
Reference Range Information
Performing Location Reference Range
All Performing Sites Males < = 49 years: 0.0 - 2.5 ng/mL
Males 50-59 years: 0.0 - 3.5 ng/mL
Males >= 60 years: 0.0 - 4.0 ng/mL​
Interpretation
Marshfield campus PSA assay shows improved sensitivity with a lower limit of detection of <0.03 ng/mL. Results in the range of 0-2 will be reported to two decimal places enabling improved monitoring of post-prostectomy patients.​
For more information visit:
Performing Laboratory Information

Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Weston
 ​Monday through Sunday​ ​Less than 2 hours​ ​One Step Sandwich Enzyme Immunoassay/Siemens Dimension
​Neillsville​Monday through Sunday​​​Less than 2 hours​​​One Step Sandwich Enzyme Immunoassay/Siemens Dimension​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
84153 ​ ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.