Passively acquired IgG antibody from recent immune globulin administration or transfusion may result in transiently positive test results.
The presence of heterophilic antibodies or human antimouse antibodies (in patients who have received preparations of mouse monoclonal antibodies for diagnosis or therapy) in serum may interfere with the assay and cause erroneous results (false-positive or false-negative).
Specimens from individuals with anti-Escherichia coli, anti-cytomegalovirus (CMV), or hemodialysis patients may cross-react with this assay.