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22183 Alkaline Phosphatase, Total

Alkaline Phosphatase, Total
Test Code: ALKP
Synonyms/Keywords
​Alk P'tase, Phosphatase, Alkaline, ALKP​
Useful For
Alkaline phosphatase measurements are used in the diagnosis and treatment of liver, bone, parathyroid, and intestinal diseases. Serum enzyme levels of alkaline phosphatase will be increased due to enzyme induction associated with any form of biliary obstruction.  A considerable rise in ALP activity is sometimes seen in children and juveniles.  It is caused by increased osteoblast activity following accelerated bone growth.​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Plasma​/Serum Lithium -heparin Plasma Separator (PST)​, Serum Separator Tube (SST)
Lithium or Sodium-heparin Green Top (GTT), Red Top (RTT)
 
 1 mL​ 0.5 mL​ 0.5 mL whole blood​
Specimen Stability Information
Specimen Type Temperature Time
Plasma​/Serum ​ ​ Ambient​ 5 days​
Refrigerate​ 1 week​
Frozen​ 3 months​
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Chippewa Falls ​Monday through Friday​ ​Less than 2 hours​ ​IFCC standardized bichromatic rate method/Siemens Dimension
Weston​ ​Monday through Sunday​ ​Less than 2 hours​ ​​IFCC standardized bichromatic rate method/Siemens Dimension
​Eau Claire ​Monday through Sunday​ ​Less than 2 hours​ (IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
Park Falls
 ​Monday through Sunday​ ​Less than 2 hours​ ​​(IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
​Ladysmith Medical Center ​Monday through Sunday ​Less than 2 hours​ ​​(IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
​Lakeview Medical Center ​Monday through Sunday​ ​Less than 2 hours​ (IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
Marshfield​ Monday through Sunday​ Less than 2 hours​ (IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
​Minocqua ​Monday through Sunday ​Less than 2 hours​ ​​​(IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
​Neillsville​Monday through Sunday​Less than 2 hours​IFCC standardized bichromatic rate method/Siemens Dimension
​Stevens Point ​Monday through Saturday ​Less than 2 hours​​
 (IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU 
​Wisconsin Rapids ​Monday through Friday ​Less than 2 hours​ ​​​IFCC standardized bichromatic rate method/Siemens Dimension
Reference Range Information
Performing Location Reference Range
All Performing Sites Using Beckman AU Analyzers
     Both:           0 – 14 days:          80 - 245 U/L
             15 days - <1 yr:        120 - 466 U/L
                    1 - <10 yrs:       140 - 331 U/L
                  10 - <13 yrs:        126 - 414 U/L
Male:          13 - <15 yrs:        113 - 465 U/L
                  15 – <17 yrs:          80 - 328 U/L
                  17 - <19 yrs:          52 - 147 U/L
                        >=19yrs:          43 - 115 U/L
Female:      13 - <15 yrs:          54 - 252 U/L
                  15 – <17 yrs:          48 - 114 U/L
                  17 - <19 yrs:            42 - 85 U/L
                              >=19yrs:            33 - 98 U/L​
All Performing Sites Using Siemens Dimension Analyzers
​0-14 days: 80 - 250 IU/L
15 days - <1 year: 120 - 475 IU/L
1 - 9 years: 140 - 340 IU/L
10 - 12 years: 130 - 420 IU/L
Male: 13 - 14 years: 115 - 470 IU/L
Male: 15 - 16 years: 80 - 335 IU/L
Male: 17 - 18 years: 50 - 150 IU/L
Female: 13 - 14 years: 55 - 250 IU/L
Female: 15 - 16 years: 50 - 115 IU/L
Female: 17 - 18 years: 45 - 95 IU/L
Adult: 19 years and older: 45 - 115 IU/L
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
84075 ​ ​ ​ ​ ​
Synonyms/Keywords
​Alk P'tase, Phosphatase, Alkaline, ALKP​
Ordering Applications
Ordering Application Description
​Centricity ​Alk. P'tase
​Cerner ​Alkaline Phosphatase
​COM ​Alkaline Phosphatase, Total
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Plasma​/Serum Lithium -heparin Plasma Separator (PST)​, Serum Separator Tube (SST)
Lithium or Sodium-heparin Green Top (GTT), Red Top (RTT)
 
 1 mL​ 0.5 mL​ 0.5 mL whole blood​
Specimen Stability Information
Specimen Type Temperature Time
Plasma​/Serum ​ ​ Ambient​ 5 days​
Refrigerate​ 1 week​
Frozen​ 3 months​
Useful For
Alkaline phosphatase measurements are used in the diagnosis and treatment of liver, bone, parathyroid, and intestinal diseases. Serum enzyme levels of alkaline phosphatase will be increased due to enzyme induction associated with any form of biliary obstruction.  A considerable rise in ALP activity is sometimes seen in children and juveniles.  It is caused by increased osteoblast activity following accelerated bone growth.​
Reference Range Information
Performing Location Reference Range
All Performing Sites Using Beckman AU Analyzers
     Both:           0 – 14 days:          80 - 245 U/L
             15 days - <1 yr:        120 - 466 U/L
                    1 - <10 yrs:       140 - 331 U/L
                  10 - <13 yrs:        126 - 414 U/L
Male:          13 - <15 yrs:        113 - 465 U/L
                  15 – <17 yrs:          80 - 328 U/L
                  17 - <19 yrs:          52 - 147 U/L
                        >=19yrs:          43 - 115 U/L
Female:      13 - <15 yrs:          54 - 252 U/L
                  15 – <17 yrs:          48 - 114 U/L
                  17 - <19 yrs:            42 - 85 U/L
                              >=19yrs:            33 - 98 U/L​
All Performing Sites Using Siemens Dimension Analyzers
​0-14 days: 80 - 250 IU/L
15 days - <1 year: 120 - 475 IU/L
1 - 9 years: 140 - 340 IU/L
10 - 12 years: 130 - 420 IU/L
Male: 13 - 14 years: 115 - 470 IU/L
Male: 15 - 16 years: 80 - 335 IU/L
Male: 17 - 18 years: 50 - 150 IU/L
Female: 13 - 14 years: 55 - 250 IU/L
Female: 15 - 16 years: 50 - 115 IU/L
Female: 17 - 18 years: 45 - 95 IU/L
Adult: 19 years and older: 45 - 115 IU/L
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Chippewa Falls ​Monday through Friday​ ​Less than 2 hours​ ​IFCC standardized bichromatic rate method/Siemens Dimension
Weston​ ​Monday through Sunday​ ​Less than 2 hours​ ​​IFCC standardized bichromatic rate method/Siemens Dimension
​Eau Claire ​Monday through Sunday​ ​Less than 2 hours​ (IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
Park Falls
 ​Monday through Sunday​ ​Less than 2 hours​ ​​(IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
​Ladysmith Medical Center ​Monday through Sunday ​Less than 2 hours​ ​​(IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
​Lakeview Medical Center ​Monday through Sunday​ ​Less than 2 hours​ (IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
Marshfield​ Monday through Sunday​ Less than 2 hours​ (IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
​Minocqua ​Monday through Sunday ​Less than 2 hours​ ​​​(IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU
​Neillsville​Monday through Sunday​Less than 2 hours​IFCC standardized bichromatic rate method/Siemens Dimension
​Stevens Point ​Monday through Saturday ​Less than 2 hours​​
 (IFCC), PNPP, AMP Buffer, Rate Assay/Beckman AU 
​Wisconsin Rapids ​Monday through Friday ​Less than 2 hours​ ​​​IFCC standardized bichromatic rate method/Siemens Dimension
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
84075 ​ ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.