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22312 Glomerular Basement Membrane Antibodies

Glomerular Basement Membrane Antibodies
Test Code: GBM
Synonyms/Keywords
 Anti-GBM, Basement membrane, GBM​
Useful For
Detects IgG autoantibodies against the glomerular basement membrane (GBM), specifically the C-terminal end of type IV collagen. In conjuction with clinical findings of lung hemorrhage and rapidly progressive renal failure, autoantibodies to GBM support the diagnosis of Goodpasture's syndrome. GBM autoantibodes also may occur in other glomerular diseases.​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) or Serum Separator Tube (SST) ​ ​ 0.5 mL​ 0.5 mL​ 0.2 mL​
Collection Processing Instructions

​Separate serum from cells within 2 hours of collection.

Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ Refrigerate​ 7 days​
Frozen > 7 days​
Rejection Criteria
Gross lipemia
Gross hemolysis​
Heat inactivated samples​
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200​
Reference Range Information
Performing Location Reference Range
Marshfield ​ Negative <1.0 ​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
83516 ​ ​ ​ ​
Synonyms/Keywords
 Anti-GBM, Basement membrane, GBM​
Ordering Applications
Ordering Application Description
​Centricity ​Glomerular Basement Membrance AB
​Cerner ​Glomerular Basement Membrane Antibodies
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) or Serum Separator Tube (SST) ​ ​ 0.5 mL​ 0.5 mL​ 0.2 mL​
Collection Processing

​Separate serum from cells within 2 hours of collection.

Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ Refrigerate​ 7 days​
Frozen > 7 days​
Rejection Criteria
Gross lipemia
Gross hemolysis​
Heat inactivated samples​
Useful For
Detects IgG autoantibodies against the glomerular basement membrane (GBM), specifically the C-terminal end of type IV collagen. In conjuction with clinical findings of lung hemorrhage and rapidly progressive renal failure, autoantibodies to GBM support the diagnosis of Goodpasture's syndrome. GBM autoantibodes also may occur in other glomerular diseases.​
Reference Range Information
Performing Location Reference Range
Marshfield ​ Negative <1.0 ​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
83516 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.