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22381 Bone Marrow Differential

Bone Marrow Differential
Test Code: B.M.
Synonyms/Keywords
​Bone Marrow Biopsy, Aspirate
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No​Bone Marrow Aspirate
10 aspirate smears and 4 touch prep smear
5-6 aspirate smears and 2 touch prep smear
Collection Processing Instructions

Marshfield - Call Lab-24 Hour Services (ext.16383) to notify department that a Bone Marrow is requested. Provide department with patient information and test requests to include Flow Cytometry, Cytogenetics and miscellaneous testing. Technologist prepares approximately 10 bone marrow aspirate smears and 4 touch prep smears, collects for other testing and places the aspirate clot and biopsy/core specimens in 10% buffered formalin fixative. 

 

Other Facilities - Call Lab-24 Hour Services at 800-222-5835 (ext. 16383) when sending a bone marrow specimen. Department will take information for Flow Cytometry and Cytogenetics, if applicable. 
Submit: 
1) At least 4 bone marrow aspirate smears and 2 touch prep smears in a slide holder. 
2) A peripheral EDTA blood smear and results of a recent Hemogram (CBC) and differential. 
3) Clot and core specimens in 10 mL of 10% buffered formalin fixative. Parafilm containers and place containers in a biohazard bag - Keep fixative vials separate from smears as fixative fumes can damage smears. 
4) A completed Bone Marrow Report form (or requisition form) for the bone marrow studies and a completed Histology Test Requisition form for the clot and core specimens. Provide patient information, diagnosis, specimen/collection information and test(s) requested. ​


Specimen Stability Information
Specimen Type Temperature Time
​Bone Marrow Smear ​Ambient 4 Weeks​
Rejection Criteria

​​Check with performing department prior to rejection. Samples may be reported with additional comments up to 24 hours.

Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Marshfield​Monday through Friday​3 days​Histochemical Stains/Manual Light Microscopy
Reference Range Information
Performing Location Reference Range
Marshfield ​Interpretive Report
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
85097​ Interp​
88313​ Stain, Group ll​
88305​ Cell block​

​​85060
​Differential
Synonyms/Keywords
​Bone Marrow Biopsy, Aspirate
Ordering Applications
Ordering Application Description
​Cerner
​Powerplan should be used
Untitled.pngPathology Bone Marrow Adult Specimen Collection
Untitled.pngPathology Bone Marrow Pediatric Specimen Collection
​4medica
​B.M.
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​No​Bone Marrow Aspirate
10 aspirate smears and 4 touch prep smear
5-6 aspirate smears and 2 touch prep smear
Collection Processing

Marshfield - Call Lab-24 Hour Services (ext.16383) to notify department that a Bone Marrow is requested. Provide department with patient information and test requests to include Flow Cytometry, Cytogenetics and miscellaneous testing. Technologist prepares approximately 10 bone marrow aspirate smears and 4 touch prep smears, collects for other testing and places the aspirate clot and biopsy/core specimens in 10% buffered formalin fixative. 

 

Other Facilities - Call Lab-24 Hour Services at 800-222-5835 (ext. 16383) when sending a bone marrow specimen. Department will take information for Flow Cytometry and Cytogenetics, if applicable. 
Submit: 
1) At least 4 bone marrow aspirate smears and 2 touch prep smears in a slide holder. 
2) A peripheral EDTA blood smear and results of a recent Hemogram (CBC) and differential. 
3) Clot and core specimens in 10 mL of 10% buffered formalin fixative. Parafilm containers and place containers in a biohazard bag - Keep fixative vials separate from smears as fixative fumes can damage smears. 
4) A completed Bone Marrow Report form (or requisition form) for the bone marrow studies and a completed Histology Test Requisition form for the clot and core specimens. Provide patient information, diagnosis, specimen/collection information and test(s) requested. ​


Specimen Stability Information
Specimen Type Temperature Time
​Bone Marrow Smear ​Ambient 4 Weeks​
Rejection Criteria

​​Check with performing department prior to rejection. Samples may be reported with additional comments up to 24 hours.

Reference Range Information
Performing Location Reference Range
Marshfield ​Interpretive Report
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Marshfield​Monday through Friday​3 days​Histochemical Stains/Manual Light Microscopy
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
85097​ Interp​
88313​ Stain, Group ll​
88305​ Cell block​

​​85060
​Differential
For most current information refer to the Marshfield Laboratory online reference manual.