Skip Ribbon Commands
Skip to main content
Sign In
Navigate Up

22392 Caffeine (CAFF)

Caffeine (CAFF)
Test Code: MISC
Useful For
Monitoring therapy in neonates
Assessing toxicity in neonates
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ Serum Separator Tube (SST) ​Red Top Tube (RTT) 0.5 mL​ ​0.25 mL ​
Collection Processing Instructions

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.

Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ Frozen (preferred)​ ​28 days
​Ambient ​72 hours
​Refrigerated 72 hours
Rejection Criteria
Gross Hemolysis
Interference

​This assay is not intended to detect levels in adults. 

Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentation
Mayo Clinic Laboratories​​
Monday through Saturday
1 day
 Enzyme Multiplied Immunoassay Technique (EMIT)
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
Performing Location Reference Range
Mayo Clinic Laboratories​​
Therapeutic: 8.0-20.0 mcg/mL
Critical value: > or =30 mcg/mL
Interpretation
Optimal pharmacologic response occurs when the serum level is in the range of 8.0 to 20.0 mcg/mL.
Toxicity in neonates and adults may be seen when the serum level is above 20 mcg/mL.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​80155 ​ ​ ​ ​
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ Serum Separator Tube (SST) ​Red Top Tube (RTT) 0.5 mL​ ​0.25 mL ​
Collection Processing

1. Serum gel tubes should be centrifuged within 2 hours of collection.

2. Red-top tubes should be centrifuged and the serum aliquoted into a plastic vial within 2 hours of collection.

Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ ​ Frozen (preferred)​ ​28 days
​Ambient ​72 hours
​Refrigerated 72 hours
Rejection Criteria
Gross Hemolysis
Interference

​This assay is not intended to detect levels in adults. 

Useful For
Monitoring therapy in neonates
Assessing toxicity in neonates
Reference Range Information
Performing Location Reference Range
Mayo Clinic Laboratories​​
Therapeutic: 8.0-20.0 mcg/mL
Critical value: > or =30 mcg/mL
Interpretation
Optimal pharmacologic response occurs when the serum level is in the range of 8.0 to 20.0 mcg/mL.
Toxicity in neonates and adults may be seen when the serum level is above 20 mcg/mL.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentation
Mayo Clinic Laboratories​​
Monday through Saturday
1 day
 Enzyme Multiplied Immunoassay Technique (EMIT)
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​80155 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.