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22551 Cytomegalovirus Antibody, IgG and IgM

Cytomegalovirus Antibody, IgG and IgM
Test Code: CMV
Synonyms/Keywords
​CMV Antibody,  Anti-CMV IgG/IgM​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​Serum Separator Tube (SST) ​Red Top Tube (RTT) 1.0 mL​0.5 mL​0.5 mL​
Collection Processing Instructions

Specimens collected in gel-barrier tubes should be centrifuged within one hour of collection.

Specimens collected in gel-barrier tubes must be removed from the primary tube prior to transporting to Marshfield. Do not send primary collection tube.

Serum from samples collected in an RTT must be removed from the clot within one hour for storage or transport.
Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ Refrigerate​d
 7 days​
Frozen​ > 7 days​
Rejection Criteria

Hemolyzed specimens​, Lipemic specimens

Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday and Friday​ 1 day​ Multiplex Immunoassay/Biorad Bioplex 2200  ​
Reference Range Information
Performing Location Reference Range
Marshfield​

IgM: Negative

IgG: Negative ​

Interpretation
A positive IgG generally indicates infection with CMV at some time. The simultaneous detection of IgM antibodies signifies recent infection or reactivation of latent infection.
 
General interpretive guidelines:
IgG Negative: Not infected or very early infection
IgG Positive: Infected
IgG Positive / IgM Negative: Prior exposure at indeterminate time.
IgG Positive / IgM Positive: Suggests acute infection.
IgG Negative / IgM Positive: Early disease, re-activation, or false-positive IgM. Repeat in 2-3 weeks.
Equivocal Results: Indeterminate. Retest if clinically indicated.​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86644​ ​ 1​ CMV IgG​ ​
86645​ ​ ​1 CMV IgM ​ ​
Synonyms/Keywords
​CMV Antibody,  Anti-CMV IgG/IgM​
Ordering Applications
Ordering Application Description
​Cerner ​Cytomegalovirus Antibody IgG and IgM
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​Serum Separator Tube (SST) ​Red Top Tube (RTT) 1.0 mL​0.5 mL​0.5 mL​
Collection Processing

Specimens collected in gel-barrier tubes should be centrifuged within one hour of collection.

Specimens collected in gel-barrier tubes must be removed from the primary tube prior to transporting to Marshfield. Do not send primary collection tube.

Serum from samples collected in an RTT must be removed from the clot within one hour for storage or transport.
Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​ Refrigerate​d
 7 days​
Frozen​ > 7 days​
Rejection Criteria

Hemolyzed specimens​, Lipemic specimens

Reference Range Information
Performing Location Reference Range
Marshfield​

IgM: Negative

IgG: Negative ​

Interpretation
A positive IgG generally indicates infection with CMV at some time. The simultaneous detection of IgM antibodies signifies recent infection or reactivation of latent infection.
 
General interpretive guidelines:
IgG Negative: Not infected or very early infection
IgG Positive: Infected
IgG Positive / IgM Negative: Prior exposure at indeterminate time.
IgG Positive / IgM Positive: Suggests acute infection.
IgG Negative / IgM Positive: Early disease, re-activation, or false-positive IgM. Repeat in 2-3 weeks.
Equivocal Results: Indeterminate. Retest if clinically indicated.​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday and Friday​ 1 day​ Multiplex Immunoassay/Biorad Bioplex 2200  ​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86644​ ​ 1​ CMV IgG​ ​
86645​ ​ ​1 CMV IgM ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.