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22608 Immune Complexes, C1q Binding (096933)

Immune Complexes, C1q Binding (096933)
Test Code: MISC
Synonyms/Keywords
C1q Binding, C1q Binding Test, C1q Immune Complexes, Circulating Immune Complexes, Complement C1q Immune Complexes, Immune Complex Detection by C1q
Useful For
Monitor immune complex disease (ie, lupus, glomerulonephritis, serum hepatitis, arthritis, vasculitis),
Monitor progress of some malignancies
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​1 mL ​0.1 mL ​
Collection Processing Instructions
Separate serum from cells within 30 minutes of collection and freeze serum in plastic tube immediately.​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ Refrigerated ​7 days
Frozen (preferred) >7 days​
Rejection Criteria
Hemolysis
Avoid repeated thawing and freezing
Interference

​Heating specimen for thawing may give false-positive results.

Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
LabCorp of America​ Tuesday and Thursday​ 4-8 days Enzyme immunoassay (EIA)​
Reference Lab
LabCorp of America
Test Information

​Circulating immune complexes can be demonstrated in rheumatic, infectious, and neoplastic diseases, as well as most immunologically mediated illnesses (inflammatory bowel disease, thrombotic thrombocytopenic purpura). The 1981 WHO/IUIS survey of laboratory tests in clinical immunology concluded that the detection of circulating immune complexes is not essential to any specific diagnosis.

Reference Range Information
Performing Location Reference Range
LabCorp of America​

Negative: <4.4 μg Eq/mL

Equivocal: 4.4-10.7 μg Eq/mL

Positive: >10.7 μg Eq/mL

Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86332 ​ ​ ​ ​
Synonyms/Keywords
C1q Binding, C1q Binding Test, C1q Immune Complexes, Circulating Immune Complexes, Complement C1q Immune Complexes, Immune Complex Detection by C1q
Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ ​Red Top Tube (RTT) ​Serum Separator Tube (SST) ​1 mL ​0.1 mL ​
Collection Processing
Separate serum from cells within 30 minutes of collection and freeze serum in plastic tube immediately.​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ Refrigerated ​7 days
Frozen (preferred) >7 days​
Rejection Criteria
Hemolysis
Avoid repeated thawing and freezing
Interference

​Heating specimen for thawing may give false-positive results.

Useful For
Monitor immune complex disease (ie, lupus, glomerulonephritis, serum hepatitis, arthritis, vasculitis),
Monitor progress of some malignancies
Reference Range Information
Performing Location Reference Range
LabCorp of America​

Negative: <4.4 μg Eq/mL

Equivocal: 4.4-10.7 μg Eq/mL

Positive: >10.7 μg Eq/mL

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
LabCorp of America​ Tuesday and Thursday​ 4-8 days Enzyme immunoassay (EIA)​
Reference Lab
LabCorp of America
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86332 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.