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Hepatitis B is a viral illness that is transmitted through blood and other body fluids. Both acute and chronic stages occur, with the frequency of progression to chronicity declining with age at time of infection. Chronic hepatitis B often leads to cirrhosis and hepatocellular carcinoma. Hepatitis B is a vaccine-preventable disease.
Limitations: • The results determined by different assays from different manufacturers can vary due to differences in assay specificities and cannot be used interchangeably. • It is recognized that the current methods for the detection of hepatitis B surface antigen may not detect all potentially infected individuals. A nonreactive test result does not exclude the possibility of exposure to or infection with hepatitis B virus. A nonreactive test result in individuals with prior exposure to hepatitis B may be due to antigen levels below the detection limit of this assay or lack of antigen reactivity to the antibodies in this assay. • Assay performance characteristics have not been established in populations of immunocompromised or immunosuppressed patients.
The presence of hepatitis B surface antigen indicates ongoing acute or chronic hepatitis B infection.
A result of a single hepatitis B lab study should be interpreted with caution.
a. Ag. Hepatitis B Surface
b. Hep. B Surf Antigen (HBsAg)