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22975 Prolactin

Prolactin
Test Code: PROLAC
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​ Serum Separator Tube (SST) Red Top Tube (RTT)​, Lithium-heparin Plasma Separator Tube (PST)​ 0.5 mL​ 0.4 mL​ 0.3 mL​
Collection Processing Instructions
Samples collected in a RTT must be removed from the clot within 1 hour for storage or transport. Samples collected in SST or PST must be removed from the primary tube within 4 hours for transport.​
Specimen Stability Information
Specimen Type Temperature Time
Serum​/Plasma Refrigerated​ 48 hours​
Frozen​ 30 days​
Interference
Human Anti-Murine Antibodies (HAMA) may develop leading to test interference in patients receiving murine-based agents for chemotherapy or tumor-imaging studies.​
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​
 Less than 2 hours​ Two-site Sandwich Immunoassay using Direct Chemiluminometric Technology/Siemens Centaur
Reference Range Information
Performing Location Reference Range
Marshfield​
Female (non-pregnant): 2.8 - 29.2 ng/mL 
            (pregnant):  9.7 - 208.5 ng/mL  
            (post-menopausal):  1.8 - 20.3 ng/mL
 
Male: 2.1 - 17.7 ng/mL​
 
Interpretation
Highest levels are seen in the morning 3-4 hours after awakening with levels decreasing 20-40% later in the afternoon. Elevations are seen in pregnancy and postpartum lactation as well as with physical exercise and stress. Large (5-10 fold) increases are usually associated with a prolactin-secreting tumor. ​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
84146​ ​ ​ ​ ​
Ordering Applications
Ordering Application Description
​Centricity ​Prolactin
​Cerner ​Prolactin Level
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​ Serum Separator Tube (SST) Red Top Tube (RTT)​, Lithium-heparin Plasma Separator Tube (PST)​ 0.5 mL​ 0.4 mL​ 0.3 mL​
Collection Processing
Samples collected in a RTT must be removed from the clot within 1 hour for storage or transport. Samples collected in SST or PST must be removed from the primary tube within 4 hours for transport.​
Specimen Stability Information
Specimen Type Temperature Time
Serum​/Plasma Refrigerated​ 48 hours​
Frozen​ 30 days​
Interference
Human Anti-Murine Antibodies (HAMA) may develop leading to test interference in patients receiving murine-based agents for chemotherapy or tumor-imaging studies.​
Reference Range Information
Performing Location Reference Range
Marshfield​
Female (non-pregnant): 2.8 - 29.2 ng/mL 
            (pregnant):  9.7 - 208.5 ng/mL  
            (post-menopausal):  1.8 - 20.3 ng/mL
 
Male: 2.1 - 17.7 ng/mL​
 
Interpretation
Highest levels are seen in the morning 3-4 hours after awakening with levels decreasing 20-40% later in the afternoon. Elevations are seen in pregnancy and postpartum lactation as well as with physical exercise and stress. Large (5-10 fold) increases are usually associated with a prolactin-secreting tumor. ​
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Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​
 Less than 2 hours​ Two-site Sandwich Immunoassay using Direct Chemiluminometric Technology/Siemens Centaur
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
84146​ ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.