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23205 Oxcarbazepine Metabolite

Oxcarbazepine Metabolite
Test Code: OXCAR
Synonyms/Keywords
Trileptal, Monohydroxycarbamazepine, MHC, 10-hydroxy-10,11 dihydrocarbamazepine​
Useful For
This test is useful for monitoring oxcarbazepine (anticonvulsant) therapy​
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No​ Serum Red Top Tube (RTT)​ 0.5 mL​ 0.5 mL​ 0.3 mL​
Collection Processing Instructions
Indicate collection time.​
Specimen Stability Information
Specimen Type Temperature Time
​ Serum ​Ambient ​48 hrs
Refrigerate​ 2 weeks
Frozen 2 weeks
Rejection Criteria
​​Specimens collected in serum or plasma separator tubes
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday, Wednesday, Friday​ 1 day​
UPLC MS/MS - Waters Acquity UPLC, XEVO TQ-S Tandem Mass Spectrometry System
Samples must be in performing department by 8am on day of testing for results the same day.​ ​ ​ ​​ ​
Testing may be batched and set up on alternative days of the week as needed.
Test Information
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.
Reference Range Information
Performing Location Reference Range
Marshfield​

Trough concentration: 6-10 ug/mL

Peak concentration: less than 40 ug/mL

Critical value: See critical value list of current critical values​

Interpretation

Optimal response to oxcarbazepine generally occurs when trough concentration is in the range of 6-10 ug/mL.  Peak concentration should be less than 40 ug/mL.

Trough concentrations are most accurate and recommended for therapeutic drug monitoring. Preferably obtained just before the next dose.​

Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
80183
Classification
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.
Synonyms/Keywords
Trileptal, Monohydroxycarbamazepine, MHC, 10-hydroxy-10,11 dihydrocarbamazepine​
Ordering Applications
Ordering Application Description
​Centricity ​Oxcarbazepine Metabolite
​Cerner ​Oxcarbazepine Metabolite
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No​ Serum Red Top Tube (RTT)​ 0.5 mL​ 0.5 mL​ 0.3 mL​
Collection Processing
Indicate collection time.​
Specimen Stability Information
Specimen Type Temperature Time
​ Serum ​Ambient ​48 hrs
Refrigerate​ 2 weeks
Frozen 2 weeks
Rejection Criteria
​​Specimens collected in serum or plasma separator tubes
Useful For
This test is useful for monitoring oxcarbazepine (anticonvulsant) therapy​
Reference Range Information
Performing Location Reference Range
Marshfield​

Trough concentration: 6-10 ug/mL

Peak concentration: less than 40 ug/mL

Critical value: See critical value list of current critical values​

Interpretation

Optimal response to oxcarbazepine generally occurs when trough concentration is in the range of 6-10 ug/mL.  Peak concentration should be less than 40 ug/mL.

Trough concentrations are most accurate and recommended for therapeutic drug monitoring. Preferably obtained just before the next dose.​

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday, Wednesday, Friday​ 1 day​
UPLC MS/MS - Waters Acquity UPLC, XEVO TQ-S Tandem Mass Spectrometry System
Samples must be in performing department by 8am on day of testing for results the same day.​ ​ ​ ​​ ​
Testing may be batched and set up on alternative days of the week as needed.
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
80183
Classification
This test was developed and its performance characteristics determined by Marshfield Labs.  It has not been cleared or approved by the US Food and Drug Administration.  This test is used for clinical purposes.  It should not be regarded as investigational or for research.
For most current information refer to the Marshfield Laboratory online reference manual.