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23300 Allergen Panel, Food (FOOD6)

Allergen Panel, Food (FOOD6)
Test Code: ALFODSO
Synonyms/Keywords
​Codfish, Cow, Egg White, IgE-Antibodies Multi-Allergen, Milk, Peanut, Soybean, Wheat
Test Components
Includes testing for codfish, egg white, cows milk, peanut, soybean, and wheat allergen​
Useful For
​

Establishing a diagnosis of an allergy to codfish, cow's milk, egg white, peanut, soybean, and wheat 

Defining the allergen responsible for eliciting signs and symptoms

Identifying allergens:

-Responsible for allergic disease and/or anaphylactic episode

-To confirm sensitization prior to beginning immunotherapy

-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens

Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in patients in whom the medical management does not depend upon identification of allergen specificity.

Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ Serum Separator Tube (SST) Red Top Tube (RTT) ​0.5 mL
0.3 mL
 ​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ Refrigerated (preferred)​ ​14 days
​Frozen ​90 days
Interference

Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and results must be interpreted in the clinical context.

False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.

Since only one result is generated for this panel, individual (single) allergen responses cannot be identified. When this panel is positive, follow-up testing is required to differentiate between individual allergens in the panel.

Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentation
Mayo Clinic Laboratories​ Monday through Friday
1 to 3 days
Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab
Mayo Clinic Laboratories
Reference Range Information

Performing LocationReference Range













Mayo Clinic Laboratories
ClassIgE kU/LInterpretation
0<0.10Negative
0/1 0.10-0.34Borderline/equivocal
10.35-0.69Equivocal
20.70-3.49Positive
33.50-17.4Positive
417.5-49.9Strongly positive
550.0-99.9Strongly positive
6> or =100Strongly positive

Reference values apply to all ages.​


Interpretation

Positive results indicate the possibility of allergic disease induced by one or more allergens present in the multi-allergen cap.

Negative results may rule out allergy, except in rare cases of allergic disease induced by exposure to a single allergen.

Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.

The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.

Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86003​ ​ ​ ​ ​
Synonyms/Keywords
​Codfish, Cow, Egg White, IgE-Antibodies Multi-Allergen, Milk, Peanut, Soybean, Wheat
Test Components
Includes testing for codfish, egg white, cows milk, peanut, soybean, and wheat allergen​
Ordering Applications
Ordering Application Description
​Cerner ​Allergen, Panel Food (FOOD6)
​COM ​Allergen Panel, Food #6 (FOOD6)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Serum​ Serum Separator Tube (SST) Red Top Tube (RTT) ​0.5 mL
0.3 mL
 ​
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ Refrigerated (preferred)​ ​14 days
​Frozen ​90 days
Interference

Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and results must be interpreted in the clinical context.

False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.

Since only one result is generated for this panel, individual (single) allergen responses cannot be identified. When this panel is positive, follow-up testing is required to differentiate between individual allergens in the panel.

Useful For
​

Establishing a diagnosis of an allergy to codfish, cow's milk, egg white, peanut, soybean, and wheat 

Defining the allergen responsible for eliciting signs and symptoms

Identifying allergens:

-Responsible for allergic disease and/or anaphylactic episode

-To confirm sensitization prior to beginning immunotherapy

-To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens

Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in patients in whom the medical management does not depend upon identification of allergen specificity.

Test Components
Includes testing for codfish, egg white, cows milk, peanut, soybean, and wheat allergen​
Reference Range Information

Performing LocationReference Range













Mayo Clinic Laboratories
ClassIgE kU/LInterpretation
0<0.10Negative
0/1 0.10-0.34Borderline/equivocal
10.35-0.69Equivocal
20.70-3.49Positive
33.50-17.4Positive
417.5-49.9Strongly positive
550.0-99.9Strongly positive
6> or =100Strongly positive

Reference values apply to all ages.​


Interpretation

Positive results indicate the possibility of allergic disease induced by one or more allergens present in the multi-allergen cap.

Negative results may rule out allergy, except in rare cases of allergic disease induced by exposure to a single allergen.

Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.

The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentation
Mayo Clinic Laboratories​ Monday through Friday
1 to 3 days
Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86003​ ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.