Pain Clinic Drugs with Confirmation

Test Code: PCS10

Overview
Ordering
Specimen
Performing
Clinical/Interpretive
Contacts
Coding

Synonyms/Keywords

Amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, methadone, opiates, oxycodone, buprenorphine, Clonazepam, Temazepam, Diazepam, Chlordiazepoxide, Alprazolam, Flunitrazepam, Flurazepam, Nordiazepam, Chlorazepate, Marijuana, THC, Benzoylecgonine, Cocaine, Hydromorphone, Hydrocodone, Morphine, Codeine, Oxymorphone, Oxycodone, Oxycontin, Vicodin, Amines

Test Components

Immunoassay screen with quantitative confirmation by liquid chromatography methods (when needed) for the following drug classes or method groups: amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, methadone, opiate method group, oxycodone method group, and buprenorphine. Test also includes specimen validity testing (creatinine) to detect adulteration, dilution, or substitution of the specimen.

Immunoassay screen for ethanol with quantitative result.

The immunoassay screening test for the Benzodiazepines drug class does not detect Lorazepam or Clonazepam well. If either of these drugs are suspected, please order the test “Benzodiazepines, Urine, Confirm Only by LC/MSMS” in addition to this test to insure detection if present.

Useful For

The detection of drug classes listed in this survey is useful for compliance monitoring and identification of abuse.

Specimen Requirements

Fasting Required	Specimen Type	Preferred Container/Tube	Acceptable Container/Tube	Specimen Volume	Specimen Minimum Volume (allows for 1 repeat)	Pediatric Minimum Volume (no repeat)
No	Urine	Sage urine collection container	Sterile plastic container with no preservatives	10 mL	8 mL	5 mL

Specimen Stability Information

Specimen Type	Temperature	Time
Urine	Refrigerate (Preferred)	30 days
	Ambient	7 days
	Frozen	30 days

Performing Laboratory Information

Performing Location	Day(s) Test Performed	Analytical Time	Methodology/Instrumentation
Marshfield	Monday through Friday	If no confirmatory work is required: 1 day If confirmatory work is required: 4 days	Immunoassay by AU680 Chemistry Analyzer with Emit Immunoassay followed by quantitative confirmation by LC-MS-QToF, and/or LC-MS/MS (if needed)

Test Information

This test was developed and its performance characteristics determined by Marshfield Labs. It has not been cleared or approved by the US Food and Drug Administration. This test is used for clinical purposes. It should not be regarded as investigational or for research.

This test is designed to support medical, not forensic, purposes. The detection of drugs listed in this survey is to be used for compliance monitoring and identification of abuse.

This test will detect the following drug classes or method groups: amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, methadone, opiate method group, oxycodone method group, and buprenorphine at and above cut-off levels.

If the screen is positive, this test also includes mass-spectrometry method confirmation. Also includes specimen validity testing (creatinine) to detect adulteration, dilution, or substitution of the specimen. Quantitative immunoassay result is reported for ethanol.

All confirmations / quantitations are charged separately as needed.

The amphetamine class includes phentermine, amphetamine, methamphetamine, ephedrine, pseudoephedrine, MDA, MDEA, and MDMA (Ecstasy).

Barbiturates class includes butalbital, amobarbital, secobarbital, pentobarbital, and phenobarbital.

Benzodiazepines class includes desalkylflurazepam, nordiazepam, 7-aminoflunitrazepam, oxazepam, temazepam, 7-aminoclonazepam, lorazepam, alpha-hydroxyalprazolam, and diazepam.

Buprenorphine method group includes buprenorphine and norpbuprenorphine.

The methadone method group includes parent methadone and EDDP (methadone metabolite).

Opiate method group includes morphine, codeine, hydrocodone, hydromorphone.

Oxycodone method group includes oxycodone and oxymorphone.

Reference Range Information

Performing Location	Reference Range
Marshfield	Negative. Positives are reported with a quantitative LCMS/MS or QToF LCMS result.

Interpretation

Current Cutoff Levels for Toxicology

For detailed interpretation information of each drug class/group, please refer to the individual confirmatory assay test codes.

Outreach CPTs

CPT	Quantity	Description	Comments
80307	1	Single Drug Class Screen
80359	1	Methylenedioxyamphetamines (MDA, MDMA)	If needed
80326	1	Amphetamines confirmation	If needed
G0480	1	Amphetamines confirmation	For Medicare/Medicaid (If needed)
80345	1	Barbiturates confirmation	If needed
G0480	1	Barbiturates confirmation	For Medicare/Medicaid (If needed)
80346	1	Benzodiazepine confirmation	If needed
G0480	1	Benzodiazepine confirmation	For Medicare/Medicaid (If needed)
80348	1	Buprenorphine confirmation	If needed
G0480	1	Buprenorphine confirmation	For Medicare/Medicaid (If needed)
80349	1	Cannabinoids confirmation	If needed
G0480	1	Cannabinoids confirmation	For Medicare/Medicaid (If needed)
80353	1	Cocaine confirmation	If needed
G0480	1	Cocaine confirmation	For Medicare/Medicaid (If needed)
80358	1	Methadone confirmation	If needed
G0480	1	Methadone confirmation	For Medicare/Medicaid (If needed)
80361	1	Opiate confirmation	If needed
G0480	1	Opiate confirmation	For Medicare/Medicaid (If needed)
80365	1	Oxycodone confirmation	If needed
G0480	1	Oxycodone confirmation	For Medicare/Medicaid (If needed)

Classification

Synonyms/Keywords

Test Components

Immunoassay screen for ethanol with quantitative result.

Ordering Applications

Ordering Application	Description
Cerner	Pain Clinic Drugs w/Conf., Urine

If the ordering application you are looking for is not listed, contact your local laboratory for assistance.

Specimen Requirements

Fasting Required	Specimen Type	Preferred Container/Tube	Acceptable Container/Tube	Specimen Volume	Specimen Minimum Volume (allows for 1 repeat)	Pediatric Minimum Volume (no repeat)
No	Urine	Sage urine collection container	Sterile plastic container with no preservatives	10 mL	8 mL	5 mL

Specimen Stability Information

Specimen Type	Temperature	Time
Urine	Refrigerate (Preferred)	30 days
	Ambient	7 days
	Frozen	30 days

Useful For

The detection of drug classes listed in this survey is useful for compliance monitoring and identification of abuse.

Test Components

Immunoassay screen for ethanol with quantitative result.

Reference Range Information

Performing Location	Reference Range
Marshfield	Negative. Positives are reported with a quantitative LCMS/MS or QToF LCMS result.

Interpretation

Current Cutoff Levels for Toxicology

For detailed interpretation information of each drug class/group, please refer to the individual confirmatory assay test codes.

For more information visit:

http://labtestsonline.org

Performing Laboratory Information

Performing Location	Day(s) Test Performed	Analytical Time	Methodology/Instrumentation
Marshfield	Monday through Friday	If no confirmatory work is required: 1 day If confirmatory work is required: 4 days	Immunoassay by AU680 Chemistry Analyzer with Emit Immunoassay followed by quantitative confirmation by LC-MS-QToF, and/or LC-MS/MS (if needed)

For billing questions, see Contacts

Outreach CPTs

CPT	Quantity	Description	Comments
80307	1	Single Drug Class Screen
80359	1	Methylenedioxyamphetamines (MDA, MDMA)	If needed
80326	1	Amphetamines confirmation	If needed
G0480	1	Amphetamines confirmation	For Medicare/Medicaid (If needed)
80345	1	Barbiturates confirmation	If needed
G0480	1	Barbiturates confirmation	For Medicare/Medicaid (If needed)
80346	1	Benzodiazepine confirmation	If needed
G0480	1	Benzodiazepine confirmation	For Medicare/Medicaid (If needed)
80348	1	Buprenorphine confirmation	If needed
G0480	1	Buprenorphine confirmation	For Medicare/Medicaid (If needed)
80349	1	Cannabinoids confirmation	If needed
G0480	1	Cannabinoids confirmation	For Medicare/Medicaid (If needed)
80353	1	Cocaine confirmation	If needed
G0480	1	Cocaine confirmation	For Medicare/Medicaid (If needed)
80358	1	Methadone confirmation	If needed
G0480	1	Methadone confirmation	For Medicare/Medicaid (If needed)
80361	1	Opiate confirmation	If needed
G0480	1	Opiate confirmation	For Medicare/Medicaid (If needed)
80365	1	Oxycodone confirmation	If needed
G0480	1	Oxycodone confirmation	For Medicare/Medicaid (If needed)

Classification

Return To Top

For most current information refer to the Marshfield Laboratory online reference manual.

24709 Pain Clinic Drugs with Confirmation // <![CDATA[ _spBodyOnLoadFunctionNames.push("setupPageDescriptionCallout"); // ]]>

24709 Pain Clinic Drugs with Confirmation