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24726 Pain Clinic Drugs without Confirmation

Pain Clinic Drugs without Confirmation
Test Code: PCS10WO
Synonyms/Keywords
​amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, methadone, opiates, oxycodone, buprenorphine
Test Components
​Immunoassay screen for the following drug classes or method groups:  amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, methadone, opiate method group, oxycodone, and buprenorphine.  Test also includes specimen validity testing (creatinine) to detect adulteration, dilution, or substitution of the specimen.
 
The immunoassay screening test for the Benzodiazepines drug class does not detect Lorazepam or Clonazepam well.  If either of these drugs are suspected, please order the test “Benzodiazepines, Urine, Confirm Only by LC/MSMS” in addition to this test to insure detection if present.
Useful For
​This is a screening assay performed on urine specimens and is designed to support medical, not forensic, purposes. The detection of drug classes listed in this survey is to be used for compliance monitoring and identification of abuse.  This test is intended to be used by a physician or trained provider and interpreted in the context of the patient's symptoms and history. Positive results are not definitive, and should be considered presumptive. Any presumptive positive results should be confirmed before the results are acted upon (confirmations need to be ordered separately). The advantage of this test is that it is low-cost to the patient, and in most cases will give enough information to determine if the patient is adhering to the guidelines of their particular program.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Urine​ Sage urine collection container​ Sterile plastic container with no preservatives​ 5 mL​ 1.5 mL​ 1.5 mL​
Specimen Stability Information
Specimen Type Temperature Time
Urine​ Refrigerated 
3 days​
Frozen​ >3 days​
Interference
​Immunoassay is useful in detecting truly negative samples. However, each immunoassay is more sensitive to some components of the drug class than others, and cross-reactivity of other substances can interfere or alter results. Therefore, this test is intended to be used by a physician or trained provider and interpreted in the context of the patient's symptoms and history.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Beckman DxC 700 AU/Emit Immunoassay ​
Test Information
 
This is a screening-only assay performed on urine specimens and is designed to support medical, not forensic, purposes. The detection of drug classes listed in this survey is to be used for compliance monitoring and identification of abuse.
 
This test recognizes the following drug classes utilizing immunoassay reagents: amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, methadone, opiate method group, oxycodone, and buprenorphine. Test includes specimen validity testing (creatinine) to detect adulteration, dilution, or substitution of the specimen.
 
Immunoassay is useful in detecting truly negative samples. However, each immuno​assay is more sensitive to some components of the drug class than others, and cross-reactivity of other substances can interfere or alter results. Therefore, this test is intended to be used by a physician or trained provider and interpreted in the context of the patient's symptoms and history.
 
Positive results are not definitive, and should be considered presumptive. Any presumptive positive results should be confirmed before the results are acted upon. The advantage of this test is that it is low-cost to the patient, and in most cases will give enough information to determine if the patient is adhering to the guidelines of their particular pain management program.
 
Specimens are kept for 6 business days from the screening date. If confirmation by GC or mass-spectromentry method confirmation or LC/MS/MS is desired to accurately determine what drugs the patient is positive for, please call the laboratory at 93734 within this timeframe. If specimen is available, confirmation testing can be ordered at an additional charge. For specific details of what drugs are detected in each confirmation assay, please refer to the information provided with those specific test codes or inquire with the laboratory's technical staff before ordering.​
 
The immunoassay screening test for the Benzodiazepines drug class does not detect Lorazepam or Clonazepam well.  If either of these drugs are suspected, please order the test “Benzodiazepines, Urine, Confirm Only by LC/MSMS” in addition to this test to insure detection if present.
Reference Range Information
Performing Location Reference Range
Marshfield​ Negative​
Interpretation

​Current Cutoff Levels for Toxicology

Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
80307 ​ 1 Single Drug Class​ ​
Classification
​
Synonyms/Keywords
​amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, methadone, opiates, oxycodone, buprenorphine
Test Components
​Immunoassay screen for the following drug classes or method groups:  amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, methadone, opiate method group, oxycodone, and buprenorphine.  Test also includes specimen validity testing (creatinine) to detect adulteration, dilution, or substitution of the specimen.
 
The immunoassay screening test for the Benzodiazepines drug class does not detect Lorazepam or Clonazepam well.  If either of these drugs are suspected, please order the test “Benzodiazepines, Urine, Confirm Only by LC/MSMS” in addition to this test to insure detection if present.
Ordering Applications

Ordering Application Description
​Cerner ​Pain Clinic Drugs wo/Confirmation, Urine
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Urine​ Sage urine collection container​ Sterile plastic container with no preservatives​ 5 mL​ 1.5 mL​ 1.5 mL​
Specimen Stability Information
Specimen Type Temperature Time
Urine​ Refrigerated 
3 days​
Frozen​ >3 days​
Interference
​Immunoassay is useful in detecting truly negative samples. However, each immunoassay is more sensitive to some components of the drug class than others, and cross-reactivity of other substances can interfere or alter results. Therefore, this test is intended to be used by a physician or trained provider and interpreted in the context of the patient's symptoms and history.
Useful For
​This is a screening assay performed on urine specimens and is designed to support medical, not forensic, purposes. The detection of drug classes listed in this survey is to be used for compliance monitoring and identification of abuse.  This test is intended to be used by a physician or trained provider and interpreted in the context of the patient's symptoms and history. Positive results are not definitive, and should be considered presumptive. Any presumptive positive results should be confirmed before the results are acted upon (confirmations need to be ordered separately). The advantage of this test is that it is low-cost to the patient, and in most cases will give enough information to determine if the patient is adhering to the guidelines of their particular program.
Test Components
​Immunoassay screen for the following drug classes or method groups:  amphetamines, barbiturates, benzodiazepines, cannabinoids, cocaine, ethanol, methadone, opiate method group, oxycodone, and buprenorphine.  Test also includes specimen validity testing (creatinine) to detect adulteration, dilution, or substitution of the specimen.
 
The immunoassay screening test for the Benzodiazepines drug class does not detect Lorazepam or Clonazepam well.  If either of these drugs are suspected, please order the test “Benzodiazepines, Urine, Confirm Only by LC/MSMS” in addition to this test to insure detection if present.
Reference Range Information
Performing Location Reference Range
Marshfield​ Negative​
Interpretation

​Current Cutoff Levels for Toxicology

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Beckman DxC 700 AU/Emit Immunoassay ​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
80307 ​ 1 Single Drug Class​ ​
Classification
​
For most current information refer to the Marshfield Laboratory online reference manual.