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24891 Allergen, Watermelon, IgE (WMEL)

Allergen, Watermelon, IgE (WMEL)
Test Code: ALWMESO
Synonyms/Keywords
Citrullus lanatus, Citrullus vulgaris ​
Useful For

Establishing the diagnosis of an allergy to watermelon

Defining the allergen responsible for eliciting signs and symptoms 

Identifying allergens:

- Responsible for allergic disease and/or anaphylactic episode

- To confirm sensitization prior to beginning immunotherapy

- To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens

Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in patients in whom the medical management does not depend upon identification of allergen specificity.

Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
Serum​ ​Serum Separator Tube (SST) ​Red Top Tube (RTT) ​0.5 mL
For 1 allergen: 0.3 mL/For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL dead space
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ Refrigerated (preferred)​ 14 days​
​Frozen ​90 days
Interference

Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and results must be interpreted in the clinical context.

False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.

Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Clinic Laboratories​ Monday through Friday​
1 day
Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab
Reference Range Information

Performing LocationReference Range













​Mayo Clinic Laboratories
ClassIgE kU/LInterpretation
0<0.10Negative
0/1 0.10-0.34Borderline/equivocal
10.35-0.69Equivocal
20.70-3.49Positive
33.50-17.4Positive
417.5-49.9Strongly positive
550.0-99.9Strongly positive
6> or =100Strongly positive

Reference values apply to all ages.


Interpretation
Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.
 
The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​86003
Synonyms/Keywords
Citrullus lanatus, Citrullus vulgaris ​
Ordering Applications
Ordering Application Description
​Centricity ​Allergen, Watermelon IgE
​Cerner ​None
​COM ​Allergen, Watermelon IgE
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
Serum​ ​Serum Separator Tube (SST) ​Red Top Tube (RTT) ​0.5 mL
For 1 allergen: 0.3 mL/For more than 1 allergen: (0.05 mL x number of allergens) + 0.25 mL dead space
Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ Refrigerated (preferred)​ 14 days​
​Frozen ​90 days
Interference

Some individuals with clinically insignificant sensitivity to allergens may have measurable levels of IgE antibodies in serum, and results must be interpreted in the clinical context.

False-positive results for IgE antibodies may occur in patients with markedly elevated serum IgE (>2500 kU/L) due to nonspecific binding to allergen solid phases.

Useful For

Establishing the diagnosis of an allergy to watermelon

Defining the allergen responsible for eliciting signs and symptoms 

Identifying allergens:

- Responsible for allergic disease and/or anaphylactic episode

- To confirm sensitization prior to beginning immunotherapy

- To investigate the specificity of allergic reactions to insect venom allergens, drugs, or chemical allergens

Testing for IgE antibodies is not useful in patients previously treated with immunotherapy to determine if residual clinical sensitivity exists, or in patients in whom the medical management does not depend upon identification of allergen specificity.

Reference Range Information

Performing LocationReference Range













​Mayo Clinic Laboratories
ClassIgE kU/LInterpretation
0<0.10Negative
0/1 0.10-0.34Borderline/equivocal
10.35-0.69Equivocal
20.70-3.49Positive
33.50-17.4Positive
417.5-49.9Strongly positive
550.0-99.9Strongly positive
6> or =100Strongly positive

Reference values apply to all ages.


Interpretation
Detection of IgE antibodies in serum (Class 1 or greater) indicates an increased likelihood of allergic disease as opposed to other etiologies and defines the allergens that may be responsible for eliciting signs and symptoms.
 
The level of IgE antibodies in serum varies directly with the concentration of IgE antibodies expressed as a class score or kU/L.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Mayo Clinic Laboratories​ Monday through Friday​
1 day
Fluorescence Enzyme Immunoassay (FEIA)
Reference Lab

​Marshfield Labs
1000 North Oak Avenue
Marshfield, WI 54449-5795

Laboratory Reference Services

  • Marshfield Labs Customer Service
    • Toll-free: 800-222-5835
    • Direct Dial: 715-221-6700
    • Internal: ext. 16700
    • Fax: 715-221-6215
    • Email: mlcussev@marshfieldclinic.org
    • Web Portal Helpline (technical support):866-522-2611

Billing Questions

  • Marshfield Center Patient Assistance Center (PAC)
    • Fee estimates, assistance with available government programs (e.g Badger Care): 800-782-8581 ext. 94475
    • Insurance eligibility, insurance referrals, managed care requirements that include Preadmission Review (PAR): 800-782-8581 ext. 75559
  • Patient Financial Services (PFS)
    • Marshfield Center: Billing statements(questions/concerns): 800-782-8581 ext. 90700
    • Marshfield Labs Billing Department: Billing statements, insurance eligibility/contracts, fee estimates (Non-Sendouts), credit card payments: 800-782-8581 ext. 90616
    • St. Joseph's Hospital of Marshfield (a Ministry affiliate): Internal ext. 77164
For sites other than Marshfield Center, please contact your local PAC (e.g. Diagnostic &Treatment Center, Flambeau Hospital, Lakeview Medical Center)


Toxicology Services

  • ​Toll-free: 800-222-5835
  • Direct Dial: 715-389-3734
  • Internal ext. 9-3734
  • Billing questions: 715-389-0616
  • Customer Service Email: mlcussev@marshfieldclinic.org
  • Web Portal Helpline (technical support): 866-522-2611

For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​86003
For most current information refer to the Marshfield Laboratory online reference manual. Tue Jan 07 2025 03:11:48 GMT+0000 (Coordinated Universal Time)