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24984 Bile Acids, Total Serum (BILEA)

Bile Acids, Total Serum (BILEA)
Test Code: BACIDSO
Synonyms/Keywords

​Bile Salts Total

Bile Acids, Total, Serum (BILEA)

Useful For
An aid in the evaluation of liver function
Evaluation of liver function changes before the formation of more advanced clinical signs of illness such as icterus
An aid in the determination of hepatic dysfunction as a result of chemical and environmental injury
An indicator of hepatic histological improvement in chronic hepatitis C patients responding to interferon treatment
An indicator for intrahepatic cholestasis of pregnancy
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Fasting (12 hour minimum)*​
*Infants and pregnant patients do not need to fast
 Serum​ Serum Separator Tube (SST)​ Red Top Tube (RTT) 0.5 mL​ ​0.25 mL ​
Collection Processing Instructions

Fasting (12 hour minimum).

Serum separator tubes should be centrifuged within 2 hours of collection.

​Red top tubes should be centrifuged and aliquoted within 2 hours of collection.​

Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ Refrigerated (preferred)​ ​7 days
​Frozen ​30 days
​Room temperature ​24 hours
Rejection Criteria
Gross Hemolysis
Gross Icterus
Interference

Serum total bile acids testing is generally not suitable for differentiation among the various types of liver diseases.

Total bile acids concentration is increased after meals; samples should be collected under fasting conditions.

Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentation
Mayo Clinic Laboratories​​ 
Monday through Sunday
1 to 2 days
Enzymatic
Reference Lab
Mayo Clinic Laboratories
Reference Range Information
Performing Location Reference Range
Mayo Clinic Laboratories​​
< or = 10 mcmol/L
Reference interval applies to fasting total bile acid concentrations
Interpretation
Total bile acids are metabolized in the liver and can serve as a marker for normal liver function. Increases in serum bile acids are seen in patients with acute hepatitis, chronic hepatitis, liver sclerosis, and liver cancer.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​82239 ​ ​ ​ ​
Synonyms/Keywords

​Bile Salts Total

Bile Acids, Total, Serum (BILEA)

Ordering Applications
Ordering Application Description
​COM ​Bile Acids, Total, Serum (BILEA)
​Cerner Bile Acids, Total, Serum (BILEA)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
Fasting (12 hour minimum)*​
*Infants and pregnant patients do not need to fast
 Serum​ Serum Separator Tube (SST)​ Red Top Tube (RTT) 0.5 mL​ ​0.25 mL ​
Collection Processing

Fasting (12 hour minimum).

Serum separator tubes should be centrifuged within 2 hours of collection.

​Red top tubes should be centrifuged and aliquoted within 2 hours of collection.​

Specimen Stability Information
Specimen Type Temperature Time
​Serum ​ Refrigerated (preferred)​ ​7 days
​Frozen ​30 days
​Room temperature ​24 hours
Rejection Criteria
Gross Hemolysis
Gross Icterus
Interference

Serum total bile acids testing is generally not suitable for differentiation among the various types of liver diseases.

Total bile acids concentration is increased after meals; samples should be collected under fasting conditions.

Useful For
An aid in the evaluation of liver function
Evaluation of liver function changes before the formation of more advanced clinical signs of illness such as icterus
An aid in the determination of hepatic dysfunction as a result of chemical and environmental injury
An indicator of hepatic histological improvement in chronic hepatitis C patients responding to interferon treatment
An indicator for intrahepatic cholestasis of pregnancy
Reference Range Information
Performing Location Reference Range
Mayo Clinic Laboratories​​
< or = 10 mcmol/L
Reference interval applies to fasting total bile acid concentrations
Interpretation
Total bile acids are metabolized in the liver and can serve as a marker for normal liver function. Increases in serum bile acids are seen in patients with acute hepatitis, chronic hepatitis, liver sclerosis, and liver cancer.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentation
Mayo Clinic Laboratories​​ 
Monday through Sunday
1 to 2 days
Enzymatic
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​82239 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.