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25015 Histoplasma Antigen, Quantitative, Urine (310)

Histoplasma Antigen, Quantitative, Urine (310)
Test Code: HTAGUSO
Synonyms/Keywords
​Histoplasma Capsulatum QNT AG
Useful For
​Aid in diagnosis of histoplasmosis
Monitor treatment to help determine when treatment can be discontinued
Aid in diagnosis of relapse
Specimen Requirements
Specimen Type Preferred Container/Tube Specimen Minimum Volume
(allows for 1 repeat)
Urine​ ​Sterile leakproof container 0.5 mL​
Collection Processing Instructions
​Ship to arrive Monday through Friday using a next day delivery service.  May be shipped ambient.
Specimen Stability Information
Specimen Type Temperature Time
Urine​ ​ ​ Ambient​  14 days​
​Refrigerate (preferred)  14 days​​
​Frozen  Indefinitely
Rejection Criteria
If specimen is too viscous to pipette
Tissue, Sputum, Bronchial Brushings, Stool, FNA, Biopsy, Tracheal or Bone Marrow Aspirate​
Stored in Transport Media, Fixative or Isolator Tubes​​
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Miravista Diagnostics​ Monday through Friday​ 1 day​ Quantitative Sandwich Enzyme Immunoassay (EIA)​
Reference Lab
Test Information
​Cross-reactions are seen with blastomycosis, paracoccidioidomycosis, penicilliosis, less frequently in coccidioidomycosis, rarely in aspergillosis and possibly sporotrichosis. Sputolysin, sodium hydroxide and potassium hydroxide treatment degrade the analyte detected in the assay.   

The result is not intended to be used as the sole means for the clinical diagnosis or patient management decisions.

Negative results do not exclude histoplasmosis. Testing of both urine and serum offers the highest sensitivity. Failure of the antigen to rise does not exclude relapse.

*New positives may require confirmation

Reference Range Information
​None Detected
Interpretation

​Interpretive Information: 

Positive Below the Limit of Quantification: Results above the cutoff for positivity, but below 0.4 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

Positive: 0.4-19.0 ng/mL

Positive Above the Limit of Quantification: Results greater than 19.0 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​87385
Synonyms/Keywords
​Histoplasma Capsulatum QNT AG
Ordering Applications
Ordering Application Description
​Centricity ​Histoplasma Ag, Qnt Urine
​Cerner ​Histoplasma Ag, Qnt Urine
​COM ​Histoplasma Ag, Qnt Urine
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen Type Preferred Container/Tube Specimen Minimum Volume
(allows for 1 repeat)
Urine​ ​Sterile leakproof container 0.5 mL​
Collection Processing
​Ship to arrive Monday through Friday using a next day delivery service.  May be shipped ambient.
Specimen Stability Information
Specimen Type Temperature Time
Urine​ ​ ​ Ambient​  14 days​
​Refrigerate (preferred)  14 days​​
​Frozen  Indefinitely
Rejection Criteria
If specimen is too viscous to pipette
Tissue, Sputum, Bronchial Brushings, Stool, FNA, Biopsy, Tracheal or Bone Marrow Aspirate​
Stored in Transport Media, Fixative or Isolator Tubes​​
Useful For
​Aid in diagnosis of histoplasmosis
Monitor treatment to help determine when treatment can be discontinued
Aid in diagnosis of relapse
Reference Range Information
​None Detected
Interpretation

​Interpretive Information: 

Positive Below the Limit of Quantification: Results above the cutoff for positivity, but below 0.4 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

Positive: 0.4-19.0 ng/mL

Positive Above the Limit of Quantification: Results greater than 19.0 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Miravista Diagnostics​ Monday through Friday​ 1 day​ Quantitative Sandwich Enzyme Immunoassay (EIA)​
Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)
Quantity Description Comments
​87385
For most current information refer to the Marshfield Laboratory online reference manual.