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25018 Syphilis Antibody Confirmatory Test

Syphilis Antibody Confirmatory Test
Test Code: SYPHCON
Synonyms/Keywords
Syphilis confirmatory, T. pallidum, FTA, TP-PA
Test Components
Syphilis Treponemal Antibody, Treponema pallidum Particle Agglutination (TP-PA)-if needed
Useful For
​Order this test if the patient has a positive RPR. Samples will be tested for IgG & IgM antibodies to Treponemal pallidum. In case the results of the antibody testing disagree with the RPR, another treponemal test, Treponemal pallidum Particle Agglutination (TPPA) will be performed at an additional charge.
 
NOTE: The CDC and WHO recommend both a positive antibody test against the causative agent Treponema pallidum and a positive non-treponemal test such as the Rapid Plasma Reagin (RPR) before making a serological diagnosis of syphilis.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No ​Serum
 Red Top Tube (RTT)
or Serum Separator Tube (SST)​
 ​ 1.0 mL​ 0.5 mL​ 0.5 mL​
Collection Processing Instructions

​Separate serum from cells within 2 hours of collection.

Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​
Refrigerate
 7 days
​Freeze > 7 days​​
Rejection Criteria
Gross hemolysis
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200
OR
RPR (Rapid Plasma Reagin) Flocculation Test​
Reference Range Information
Performing Location Reference Range
Marshfiel​d​ Negative​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86780 ​ 1​ Treponemal antibody test​ ​
​86780 ​ ​1 ​TP-PA (if needed) ​
Synonyms/Keywords
Syphilis confirmatory, T. pallidum, FTA, TP-PA
Test Components
Syphilis Treponemal Antibody, Treponema pallidum Particle Agglutination (TP-PA)-if needed
Ordering Applications
Ordering Application Description
​COM ​Syphilis Antibody Confirmatory Test, IgG
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
​No ​Serum
 Red Top Tube (RTT)
or Serum Separator Tube (SST)​
 ​ 1.0 mL​ 0.5 mL​ 0.5 mL​
Collection Processing

​Separate serum from cells within 2 hours of collection.

Specimen Stability Information
Specimen Type Temperature Time
Serum​ ​
Refrigerate
 7 days
​Freeze > 7 days​​
Rejection Criteria
Gross hemolysis
Useful For
​Order this test if the patient has a positive RPR. Samples will be tested for IgG & IgM antibodies to Treponemal pallidum. In case the results of the antibody testing disagree with the RPR, another treponemal test, Treponemal pallidum Particle Agglutination (TPPA) will be performed at an additional charge.
 
NOTE: The CDC and WHO recommend both a positive antibody test against the causative agent Treponema pallidum and a positive non-treponemal test such as the Rapid Plasma Reagin (RPR) before making a serological diagnosis of syphilis.
Test Components
Syphilis Treponemal Antibody, Treponema pallidum Particle Agglutination (TP-PA)-if needed
Reference Range Information
Performing Location Reference Range
Marshfiel​d​ Negative​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Multiplex Flow Immunoassay/Bio-Rad BioPlex 2200
OR
RPR (Rapid Plasma Reagin) Flocculation Test​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​86780 ​ 1​ Treponemal antibody test​ ​
​86780 ​ ​1 ​TP-PA (if needed) ​
For most current information refer to the Marshfield Laboratory online reference manual.