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25117 PTH, Intact - Other Fluids

PTH, Intact - Other Fluids
Test Code: PTH-O
Synonyms/Keywords
FNA, Fine Needle Aspirate, Parathyroid Hormone, Fluid, Cyst, PTH​
Useful For
This test is an adjunct to cytology examination of fine-needle aspiration specimens to confirm or exclude presence of parathyroid tissue in the biopsied area.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume
Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No​ Body Fluid​ ​ ​ 1.0 mL​ 0.7 mL​ 0.4 mL​
Collection Processing Instructions
Indicate the fluid type. If the specimen shows visible blood or tissue contamination, centrifuge the specimen. Transfer the supernatant to a new plastic tube. Maintain specimens refrigerated and freeze if testing not performed within 4 hours. Avoid freeze and thaw of samples. Only one freeze and thaw cycle acceptable.
Specimen Stability Information
Specimen Type Temperature Time
Body Fluid​ ​ ​ ​ Ambient​ 4 hours​
Refrigerate 8 hours​
Frozen at -20 deg Celsius​ 3 months
​Frozen at -70 deg Celsius ​> 3 months
​Fine Needle Aspirate ​ ​ ​ ​Ambient​ ​24 hours
​Refrigerate ​7 days
​Frozen at -20 deg Celsius ​3 months
​Frozen at -70 deg Celsius ​​> 3 months
Rejection Criteria
Highly viscous specimens.
Interference
Immunometric assays can be subject to interferences such as "hook effect" at very high analyte concentrations (false-low results) and heterophilic antibody interference (false-high results). If the clinical picture does not fit the laboratory result, these possibilities should be considered.
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Eau Claire ​Monday through Friday ​Less than 2 hours ​Two-site Sandwich Immunoassay using Direct Chemiluminometric Technology/Siemens Centaur ​
Marshfield​ Monday through Sunday​ Less than 2 hours
Two-site Sandwich Immunoassay using Direct Chemiluminometric Technology/Siemens Centaur ​
Reference Range Information
Performing Location Reference Range
Marshfield​ and Eau Claire

No reference ranges are available.

This test cannot distinguish between benign and malignant parathyroid tissue.​

Interpretation
PTH analysis from fine-needle aspiration biopsies (FNAB) is popularly used to discriminate thyroid tissues from enlarged parathyroid glands and also to facilitate parathyroid localization prior to surgery. Specimen collection is critical for the performance of the assay and the needle should be rinsed with a minimal volume. Comparing the results of the PTH rinse material with serum PTH is highly recommended. An elevated PTH in the serum could falsely elevate PTH in the washings if the rinse is contaminated with blood. In these cases, only PTH values significantly higher than the serum should be considered as true positives.
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​83970 ​ ​ ​ ​
Synonyms/Keywords
FNA, Fine Needle Aspirate, Parathyroid Hormone, Fluid, Cyst, PTH​
Ordering Applications
Ordering Application Description
​COM ​PTH, Intact - Other Fluids
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume
Specimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
No​ Body Fluid​ ​ ​ 1.0 mL​ 0.7 mL​ 0.4 mL​
Collection Processing
Indicate the fluid type. If the specimen shows visible blood or tissue contamination, centrifuge the specimen. Transfer the supernatant to a new plastic tube. Maintain specimens refrigerated and freeze if testing not performed within 4 hours. Avoid freeze and thaw of samples. Only one freeze and thaw cycle acceptable.
Specimen Stability Information
Specimen Type Temperature Time
Body Fluid​ ​ ​ ​ Ambient​ 4 hours​
Refrigerate 8 hours​
Frozen at -20 deg Celsius​ 3 months
​Frozen at -70 deg Celsius ​> 3 months
​Fine Needle Aspirate ​ ​ ​ ​Ambient​ ​24 hours
​Refrigerate ​7 days
​Frozen at -20 deg Celsius ​3 months
​Frozen at -70 deg Celsius ​​> 3 months
Rejection Criteria
Highly viscous specimens.
Interference
Immunometric assays can be subject to interferences such as "hook effect" at very high analyte concentrations (false-low results) and heterophilic antibody interference (false-high results). If the clinical picture does not fit the laboratory result, these possibilities should be considered.
Useful For
This test is an adjunct to cytology examination of fine-needle aspiration specimens to confirm or exclude presence of parathyroid tissue in the biopsied area.
Reference Range Information
Performing Location Reference Range
Marshfield​ and Eau Claire

No reference ranges are available.

This test cannot distinguish between benign and malignant parathyroid tissue.​

Interpretation
PTH analysis from fine-needle aspiration biopsies (FNAB) is popularly used to discriminate thyroid tissues from enlarged parathyroid glands and also to facilitate parathyroid localization prior to surgery. Specimen collection is critical for the performance of the assay and the needle should be rinsed with a minimal volume. Comparing the results of the PTH rinse material with serum PTH is highly recommended. An elevated PTH in the serum could falsely elevate PTH in the washings if the rinse is contaminated with blood. In these cases, only PTH values significantly higher than the serum should be considered as true positives.
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
​Eau Claire ​Monday through Friday ​Less than 2 hours ​Two-site Sandwich Immunoassay using Direct Chemiluminometric Technology/Siemens Centaur ​
Marshfield​ Monday through Sunday​ Less than 2 hours
Two-site Sandwich Immunoassay using Direct Chemiluminometric Technology/Siemens Centaur ​
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
​83970 ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.