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25187 Syphilis, Neonatal Screen (less than 1 month of age)

Syphilis, Neonatal Screen (less than 1 month of age)
Test Code: RPRNEO
Synonyms/Keywords
​Syphilis, RPR​
Useful For
This test is useful for the evaluation of neonates < one month of age suspected of having congenital syphilis. Positive tests will be titered.
 
Note: Positive tests will not be confirmed with a second treponemal test as recommended by the CDC for individuals over the age of one month. For the determination of syphilis serostatus in individuals > one month in age, order Syphilis Antibody IgG/IgM (SYPHAB)
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) or Serum Separator Tube (SST) ​ ​ 0.5 mL​ 0.3 mL​ 0.3 mL​
Collection Processing Instructions

​Separate serum from cells within 2 hours of collection.

Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerate​ 5 days​
Frozen > 5 days​
Rejection Criteria
Gross hemolysis
Gross lipemia
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Multiplex Flow Immunoassay/ Bio-Rad BioPlex 2200
OR
RPR (Rapid Plasma Reagin) Flocculation Test
Test Information
This semi-quantitative test is intended for testing neonates (<1 month of age) only. It does not include a confirmatory treponemal test as recommended by the CDC for individuals one month of age and above. Order Syphilis Antibody, IgG (SYPHAB) as the primary syphilis diagnostic test.​
Reference Range Information
Performing Location Reference Range
 Marshfield​ Negative​
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86593​ ​ ​ ​ ​
Synonyms/Keywords
​Syphilis, RPR​
Ordering Applications
Ordering Application Description
​Cerner ​Syphilis, Neonatal Scr <1 month
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)
No​ Serum​ Red Top Tube (RTT) or Serum Separator Tube (SST) ​ ​ 0.5 mL​ 0.3 mL​ 0.3 mL​
Collection Processing

​Separate serum from cells within 2 hours of collection.

Specimen Stability Information
Specimen Type Temperature Time
Serum​ Refrigerate​ 5 days​
Frozen > 5 days​
Rejection Criteria
Gross hemolysis
Gross lipemia
Useful For
This test is useful for the evaluation of neonates < one month of age suspected of having congenital syphilis. Positive tests will be titered.
 
Note: Positive tests will not be confirmed with a second treponemal test as recommended by the CDC for individuals over the age of one month. For the determination of syphilis serostatus in individuals > one month in age, order Syphilis Antibody IgG/IgM (SYPHAB)
Reference Range Information
Performing Location Reference Range
 Marshfield​ Negative​
For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Analytical Time Methodology/Instrumentation
Marshfield​ Monday through Friday​ 1 day​ Multiplex Flow Immunoassay/ Bio-Rad BioPlex 2200
OR
RPR (Rapid Plasma Reagin) Flocculation Test
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Comments
86593​ ​ ​ ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.