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25422 EGFR Gene Mutation, Tumor (EGFRT)

EGFR Gene Mutation, Tumor (EGFRT)
Test Code: EGF29SO
Synonyms/Keywords
EGFR
EGFR-TKI
EGFR-tyrosine kinase inhibitor
Epidermal growth factor receptor
Erlotinib
Gefitinib
Non-small cell lung cancer
NSCLC
T790M
Test Components

​When this test is ordered, slide review will always be performed at an additional charge.

Useful For
Identifying non-small cell lung cancers that may respond to epidermal growth factor receptor-tyrosine kinase inhibitor therapies.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)​​
No​ ​Tissue ​Formalin-fixed paraffin-embedded tissue block ​1 stained and 5 unstained slides ​ ​ ​
Collection Processing Instructions
Pathology report must accompany specimen in order for testing to be performed. Submit 1 slide stained with hematoxylin and eosin and 5 unstained, non-baked slides with 5-micron thick sections of the tumor tissue. 
Specimen Stability Information
Specimen Type ​​Temperature
Paraffin block ​Room Temperature ​
​Slides
Rejection Criteria

​Specimens that have been decalcified (all methods) Specimens that have not been formalin-fixed, paraffin-embedded

Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentatio​​n
​Mayo Clinic Laboratories ​Monday through Friday 5 to 7 days Polymerase Chain Reaction (PCR) Analysis
Reference Lab
Mayo Clinic Laboratories
Reference Range Information

​An interpretive report will be provided.

Interpretation

​An interpretive report will be provided. 

Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Commen​​ts
81235​ ​ ​1 ​ ​
​88381 ​ ​1 ​ ​
Synonyms/Keywords
EGFR
EGFR-TKI
EGFR-tyrosine kinase inhibitor
Epidermal growth factor receptor
Erlotinib
Gefitinib
Non-small cell lung cancer
NSCLC
T790M
Test Components

​When this test is ordered, slide review will always be performed at an additional charge.

Ordering Applications
Ordering Application Description
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting Required Specimen Type Preferred Container/Tube Acceptable Container/Tube Specimen Volume Specimen Minimum Volume
(allows for 1 repeat)		 Pediatric Minimum Volume
(no repeat)​​
No​ ​Tissue ​Formalin-fixed paraffin-embedded tissue block ​1 stained and 5 unstained slides ​ ​ ​
Collection Processing
Pathology report must accompany specimen in order for testing to be performed. Submit 1 slide stained with hematoxylin and eosin and 5 unstained, non-baked slides with 5-micron thick sections of the tumor tissue. 
Specimen Stability Information
Specimen Type ​​Temperature
Paraffin block ​Room Temperature ​
​Slides
Rejection Criteria

​Specimens that have been decalcified (all methods) Specimens that have not been formalin-fixed, paraffin-embedded

Useful For
Identifying non-small cell lung cancers that may respond to epidermal growth factor receptor-tyrosine kinase inhibitor therapies.
Test Components

​When this test is ordered, slide review will always be performed at an additional charge.

Reference Range Information

​An interpretive report will be provided.

Interpretation

​An interpretive report will be provided. 

For more information visit:
Performing Laboratory Information
Performing Location Day(s) Test Performed Report Available Methodology/Instrumentatio​​n
​Mayo Clinic Laboratories ​Monday through Friday 5 to 7 days Polymerase Chain Reaction (PCR) Analysis
Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPT Modifier
(if needed)		 Quantity Description Commen​​ts
81235​ ​ ​1 ​ ​
​88381 ​ ​1 ​ ​
For most current information refer to the Marshfield Laboratory online reference manual.