Draw blood immediately before next scheduled dose (trough specimen).
Centrifuge within 2 hours of draw.
Toxicity effects other than acute hypersensitivity infusion reactions have not been described nor correlated with infliximab concentrations.
During the initial induction phase of treatment (weeks 0, 2 and 6), steady-state has not been achieved and concentrations of infliximab may vary significantly between infusions.
Therapeutic concentrations of infliximab may vary according to the disease (eg, Crohn disease vs ulcerative colitis vs rheumatoid arthritis).