Confirming and monitoring ethylene glycol toxicity
1. Centrifuge and remove serum from red blood cells within 2 hours of draw.
2. Aliquot serum to submission container.
Please follow the STAT Ethylene Glycol and Volatiles Testing procedure in DCS for handling and transportation of the sample(s) to Mayo Clinic Laboratories.
*This test is only valid to be ordered from MCHS hospital location/branches and St. Clare's Hospital which includes the following branches: MMC Marshfield, MMC Eau Claire, Flambeau Hospital, MMC Ladysmith, MMC Rice Lake (Lakeview), MMC Neillsville and St. Clare's Hospital.
Propionic acid produced in the rare inborn error of metabolism methylmalonic acidemia may be confused with ethylene glycol in the gas chromatographic assay.
Toxic concentrations greater than or equal to 20 mg/dL may cause intoxication, central nervous system (CNS) depression, metabolic acidosis, renal damage and hypocalcemia. Ingestion of ethylene glycol can be fatal if patients do not receive immediate medical treatment.