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26199 Histoplasma Antigen, Quantitative, CSF and BF (310)

Histoplasma Antigen, Quantitative, CSF and BF (310)
Test Code: HTAGCSO
Synonyms/Keywords

​Histoplasma Capsulatum QNT AG

Useful For

​Aid in the diagnosis of histoplasmosis

Monitor treatment to help determine when treatment can be discontinued

Aid in diagnosis of relapse

Specimen Requirements
Specimen TypePreferred Container/TubeSpecimen Minimum Volume
(allows for 1 repeat)
​CSF​Sterile leak-proof container​0.8 mL
Body Fluid​​Sterile leak-proof container​0.5 mL
Collection Processing Instructions

​Ship to arrive Monday through Friday using a next day delivery service.  May be shipped ambient.

Specimen Stability Information
Specimen TypeTemperatureTime
CSF ​ ​​Ambient​14 days
Refrigerated (preferred)​​14 days
​Frozen​Indefinite
Body Fluid ​ ​​Ambient​14 days
​Refrigerated (preferred)​14 days
​Frozen​Indefinite
Rejection Criteria
If specimen is too viscous to pipette
Tissue, Sputum, Bronchial Brushings, Stool, FNA, Biopsy, Tracheal or Bone Marrow Aspirate​
Stored in Transport Media, Fixative or Isolator Tubes​
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
​Miravista Diagnostics​Monday through Friday​1 day

​Quantitative Sandwich Enzyme Immunoassay (EIA)

CSF is pre-treated to improve sensitivity

Reference Lab
Test Information
​Cross-reactions are seen with blastomycosis, paracoccidioidomycosis, penicilliosis, less frequently in coccidioidomycosis, rarely in aspergillosis and possibly sporotrichosis. Sputolysin, sodium hydroxide and potassium hydroxide treatment degrade the analyte detected in the assay.   

The result is not intended to be used as the sole means for the clinical diagnosis or patient management decisions.

Negative results do not exclude histoplasmosis.  Failure of the antigen to rise does not exclude relapse.

*New positives may require confirmation

Reference Range Information

None Detected

Interpretation

​Interpretive Information: 

Positive Below the Limit of Quantification: Results above the cutoff for positivity, but below 0.4 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

Positive: 0.4-19.0 ng/mL

Positive Above the Limit of Quantification: Results greater than 19.0 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​87385
Synonyms/Keywords

​Histoplasma Capsulatum QNT AG

Ordering Applications
Ordering ApplicationDescription
​COM​Histoplasma Ag, Qnt CSF BF
Portal​​​Histoplasma Ag, Qnt CSF BF (310)
​Centricity​​​Histoplasma Ag, Qnt CSF BF (310)
​Cerner​Histoplasma Ag, Qnt CSF BF (310)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen TypePreferred Container/TubeSpecimen Minimum Volume
(allows for 1 repeat)
​CSF​Sterile leak-proof container​0.8 mL
Body Fluid​​Sterile leak-proof container​0.5 mL
Collection Processing

​Ship to arrive Monday through Friday using a next day delivery service.  May be shipped ambient.

Specimen Stability Information
Specimen TypeTemperatureTime
CSF ​ ​​Ambient​14 days
Refrigerated (preferred)​​14 days
​Frozen​Indefinite
Body Fluid ​ ​​Ambient​14 days
​Refrigerated (preferred)​14 days
​Frozen​Indefinite
Rejection Criteria
If specimen is too viscous to pipette
Tissue, Sputum, Bronchial Brushings, Stool, FNA, Biopsy, Tracheal or Bone Marrow Aspirate​
Stored in Transport Media, Fixative or Isolator Tubes​
Useful For

​Aid in the diagnosis of histoplasmosis

Monitor treatment to help determine when treatment can be discontinued

Aid in diagnosis of relapse

Reference Range Information

None Detected

Interpretation

​Interpretive Information: 

Positive Below the Limit of Quantification: Results above the cutoff for positivity, but below 0.4 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

Positive: 0.4-19.0 ng/mL

Positive Above the Limit of Quantification: Results greater than 19.0 ng/mL fall outside the linear range of the assay. These results are positive, but not accurately quantifiable.

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
​Miravista Diagnostics​Monday through Friday​1 day

​Quantitative Sandwich Enzyme Immunoassay (EIA)

CSF is pre-treated to improve sensitivity

Reference Lab
For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
​87385
For most current information refer to the Marshfield Laboratory online reference manual.