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26222 Diabetes Mellitus Type 1 Eval, Serum (DBS1)

Diabetes Mellitus Type 1 Eval, Serum (DBS1)
Test Code: DBS1SO
Synonyms/Keywords

​Islet Cell autoantibodies

Test Components

​Diabetes Interp

GAD65

Insulin

IA-2

ZnT8

Useful For

​Distinguishing type 1 from type 2 diabetes mellitus

Identifying individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes)

Predicting future insulin requirement treatment in patients with adult-onset diabetes

Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)		Pediatric Minimum Volume
(no repeat)
​Serum​Red Top Tube (RTT)​Serum Separator Tube (SST)​4.0 mL​2.0 mL​
Specimen Stability Information
Specimen TypeTemperatureTime
​Serum​Refrigerated (preferred)​28 days
​Frozen​28 days
​Ambient​72 hours
Rejection Criteria
Gross Hemolysis
​Gross Icterus
Gross Lipemia​
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
​Mayo Medical Laboratories​

GAD65 antibody: Monday through Friday; 4 a.m.; 4 p.m.

Insulin antibodies: Monday, Wednesday, Friday; 4 a.m.

IA-2 antibody: Tuesday, Thursday; 4 a.m.

Zinc Transporter 8 Antibody: Tuesday, Thursday; 10 a.m.

​7 days

​GD65S, INAB, IA2: Radioimmunoassay (RIA)

EZNT8: Enzyme-Linked Immunosorbent Assay

DMEI: Interpretive Comments

Reference Lab
Mayo Clinic Laboratories
Reference Range Information
Performing LocationReference Range
​Mayo Medical Laboratories​

GLUTAMIC ACID DECARBOXYLASE (GAD65) ANTIBODY

< or =0.02 nmol/L

Reference values apply to all ages.

 INSULIN ANTIBODIES

< or =0.02 nmol/L

Reference values apply to all ages.

 ISLET ANTIGEN 2 (IA-2) ANTIBODY

< or =0.02 nmol/L

Reference values apply to all ages.

ZINC Transporter 8 (ZnT8) ANTIBODY

< 15.0 U/mL

Reference values apply to all ages.

Outreach CPTs
CPTModifier
(if needed)		QuantityDescriptionComments
​86337​​1​​
​86341​​3​​
Synonyms/Keywords

​Islet Cell autoantibodies

Test Components

​Diabetes Interp

GAD65

Insulin

IA-2

ZnT8

Ordering Applications
Ordering ApplicationDescription
​COM​Diabetes Mellitus Eval
​Cerner​Diabetes Mellitus Eval (DBS1)
​Centricity​Diabetes Mellitus Eval (DBS1)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)		Pediatric Minimum Volume
(no repeat)
​Serum​Red Top Tube (RTT)​Serum Separator Tube (SST)​4.0 mL​2.0 mL​
Specimen Stability Information
Specimen TypeTemperatureTime
​Serum​Refrigerated (preferred)​28 days
​Frozen​28 days
​Ambient​72 hours
Rejection Criteria
Gross Hemolysis
​Gross Icterus
Gross Lipemia​
Useful For

​Distinguishing type 1 from type 2 diabetes mellitus

Identifying individuals at risk of type 1 diabetes (including high-risk relatives of patients with diabetes)

Predicting future insulin requirement treatment in patients with adult-onset diabetes

Test Components

​Diabetes Interp

GAD65

Insulin

IA-2

ZnT8

Reference Range Information
Performing LocationReference Range
​Mayo Medical Laboratories​

GLUTAMIC ACID DECARBOXYLASE (GAD65) ANTIBODY

< or =0.02 nmol/L

Reference values apply to all ages.

 INSULIN ANTIBODIES

< or =0.02 nmol/L

Reference values apply to all ages.

 ISLET ANTIGEN 2 (IA-2) ANTIBODY

< or =0.02 nmol/L

Reference values apply to all ages.

ZINC Transporter 8 (ZnT8) ANTIBODY

< 15.0 U/mL

Reference values apply to all ages.

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
​Mayo Medical Laboratories​

GAD65 antibody: Monday through Friday; 4 a.m.; 4 p.m.

Insulin antibodies: Monday, Wednesday, Friday; 4 a.m.

IA-2 antibody: Tuesday, Thursday; 4 a.m.

Zinc Transporter 8 Antibody: Tuesday, Thursday; 10 a.m.

​7 days

​GD65S, INAB, IA2: Radioimmunoassay (RIA)

EZNT8: Enzyme-Linked Immunosorbent Assay

DMEI: Interpretive Comments

Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)		QuantityDescriptionComments
​86337​​1​​
​86341​​3​​
For most current information refer to the Marshfield Laboratory online reference manual.