MyoMarker 3 Plus Profile (FMMPP)

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Marshfield Clinic Public WebSite

Test Code: FMMPPSO

Overview
Ordering
Specimen
Performing
Clinical/Interpretive
Contacts
Coding

Synonyms/Keywords

FMMPP
Myositis Panel 3 Plus
Myomarker 3 plus
Myo Marker 3 Plus
Myo 3 Plus
Myositis

MyoMarker3 Plus Prof(FMMPP)

Useful For

The MyoMarker Panel 3 Plus can be used to assist in the diagnosis of dermatomyositis, polymyositis and the anti-synthetase syndrome. Furthermore, it allows characterization of various subsets of these disorders and offers prognostic information.

Specimen Requirements

Specimen Type	Preferred Container/Tube	Acceptable Container/Tube	Specimen Volume	Minimum Volume (no repeat)
Serum	Red Top Tube (RTT)	Serum Separator Tube (SST)	5 mL	4 mL

Collection Processing Instructions

Collection Instructions: Draw blood in a plain red-top tube(s), serum gel tube is acceptable. Spin down and send 5mL of serum refrigerated in a plastic vial.

Specimen Stability Information

Specimen Type	Temperature	Time
Serum	Refrigerated (preferred)	14 days
	Frozen	60 days
	Ambient	7 days

Rejection Criteria

Gross Hemolysis
Gross Lipemia
Gross Icterus
Any sample other than serum
Bacterial Contamination

Performing Laboratory Information

Performing Location	Day(s) Test Performed	Report Available	Methodology/Instrumentation
Mayo Clinic Laboratories forwards to Esoterix Endocrinology	Batched Weekly	12-16 days	Enzyme-Linked Immunosorbent Assay (ELISA); RIPA Gel Radiography

Reference Lab

Mayo Clinic Laboratories

Reference Range Information

Performing Location	Reference Range
Esoterix Endocrinology	Anti-PL-7 Ab, Anti-PL-12 Ab, Anti-EJ Ab, Anti-OJ Ab, Anti-SRP Ab, Anti-Mi-2-Ab, Anti-U3 RNP (Fibrillarin), Anti-U2 RNP Ab, Anti-Ku Ab: Reference Range: Negative Interpretation for: Anti-Jo-1 Ab, Anti-TIF-1gamma-Ab, Anti-MDA-5-Ab (CADM-140), Anti-NXP-2 (P140) Ab, Anti-SAE1 Ab IgG, Anti-PM/Scl-100 Ab, Anti-SS-A 52kD Ab IgG, Anti-U1-RNP Ab: Reference Range: <20 Negative: <20 units Weak Positive: 20 - 39 units Moderate Positive: 40 - 80 units Strong Positive: >80 units

Performing Location

Reference Range

Esoterix Endocrinology

Anti-PL-7 Ab, Anti-PL-12 Ab, Anti-EJ Ab, Anti-OJ Ab, Anti-SRP Ab, Anti-Mi-2-Ab, Anti-U3 RNP (Fibrillarin), Anti-U2 RNP Ab, Anti-Ku Ab:

Reference Range: Negative

Interpretation for:

Anti-Jo-1 Ab, Anti-TIF-1gamma-Ab, Anti-MDA-5-Ab (CADM-140), Anti-NXP-2 (P140) Ab, Anti-SAE1 Ab IgG, Anti-PM/Scl-100 Ab, Anti-SS-A 52kD Ab IgG, Anti-U1-RNP Ab:

Reference Range: <20

Negative: <20 units

Weak Positive: 20 - 39 units

Moderate Positive: 40 - 80 units

Strong Positive: >80 units

Outreach CPTs

CPT	Modifier (if needed)	Quantity	Description	Comments
83516		10
86235		7