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26285 Heavy Metal Occupational Exposure, with Reflex, Random, Urine (HMUOE)

Heavy Metal Occupational Exposure, with Reflex, Random, Urine (HMUOE)
Test Code: HMUOESO
Synonyms/Keywords

​Arsenic (As)
As (Arsenic)
Cadmium (Cd)
Cd (Cadmium)
Hg (Mercury)
Lead (Pb)
Mercury (Hg)
Pb (Lead)
HMUOE

Test Components

​Arsenic, Cadmium, Mercury, Lead

If arsenic concentration is greater than or equal to 10 mcg/L, then speciation will be performed at an additional charge.

Useful For

​Preferred screening test for detection of arsenic, cadmium, mercury and lead due to occupational exposure using random urine specimens

Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)		Pediatric Minimum Volume
(no repeat)
​Random Urine​Clean, plastic urine container with no metal cap or glued insert​​6 mL​3 mL​
Collection Processing Instructions

-Patient should not eat seafood for a 48-hour period prior to start of collection.

-High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Specimen Stability Information
Specimen TypeTemperatureTime
​Urine ​​Refrigerated (preferred)​7 days
​Frozen​7 days
Rejection Criteria
All specimens will be evaluated at Mayo Clinic for test suitability.
Interference

Consumption of seafood before collection of a urine specimen for arsenic testing is likely to result in a report of an elevated concentration of arsenic found in the urine, which can be clinically misleading.

Nitric acid cannot be added to either the collection or aliquot container. Nitrate interferes with the extraction procedure that would need to take place in the event of a positive arsenic result.

Performing Laboratory Information
Performing LocationDay(s) Test PerformedReport AvailableMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Saturday​1 to 4 days

ASOU, CDOU, HGOU, PBOU: ​Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

CRETR:  Enzymatic Colorimetric Assay

Reference Lab
Mayo Clinic Laboratories
Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories​

ARSENIC:

Biological Exposure Indices (BEI): <35 mcg/L at end of work week

CADMIUM:

BEI: <5.0 mcg/g creatinine

MERCURY:

BEI: <35 mcg/g creatinine

LEAD:

BEI: <150 mcg/g creatinine

Outreach CPTs
CPTModifier
(if needed)		QuantityDescriptionComments
​82175​​1​​
​82300​​1​​
​83825​​1​​
​83655​​1​​
​82570​​1​​
​82175​​1​​if needed
Synonyms/Keywords

​Arsenic (As)
As (Arsenic)
Cadmium (Cd)
Cd (Cadmium)
Hg (Mercury)
Lead (Pb)
Mercury (Hg)
Pb (Lead)
HMUOE

Test Components

​Arsenic, Cadmium, Mercury, Lead

If arsenic concentration is greater than or equal to 10 mcg/L, then speciation will be performed at an additional charge.

Ordering Applications
Ordering ApplicationDescription
​Cerner​Heavy Metals Occ Exp (HMSOR
​COM​Heavy Metals Occ Exposure w/Rflx, Random U (HMUOE)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)		Pediatric Minimum Volume
(no repeat)
​Random Urine​Clean, plastic urine container with no metal cap or glued insert​​6 mL​3 mL​
Collection Processing

-Patient should not eat seafood for a 48-hour period prior to start of collection.

-High concentrations of gadolinium and iodine are known to interfere with most metals tests. If either gadolinium- or iodine-containing contrast media has been administered, a specimen should not be collected for 96 hours.

Specimen Stability Information
Specimen TypeTemperatureTime
​Urine ​​Refrigerated (preferred)​7 days
​Frozen​7 days
Rejection Criteria
All specimens will be evaluated at Mayo Clinic for test suitability.
Interference

Consumption of seafood before collection of a urine specimen for arsenic testing is likely to result in a report of an elevated concentration of arsenic found in the urine, which can be clinically misleading.

Nitric acid cannot be added to either the collection or aliquot container. Nitrate interferes with the extraction procedure that would need to take place in the event of a positive arsenic result.

Useful For

​Preferred screening test for detection of arsenic, cadmium, mercury and lead due to occupational exposure using random urine specimens

Test Components

​Arsenic, Cadmium, Mercury, Lead

If arsenic concentration is greater than or equal to 10 mcg/L, then speciation will be performed at an additional charge.

Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories​

ARSENIC:

Biological Exposure Indices (BEI): <35 mcg/L at end of work week

CADMIUM:

BEI: <5.0 mcg/g creatinine

MERCURY:

BEI: <35 mcg/g creatinine

LEAD:

BEI: <150 mcg/g creatinine

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedReport AvailableMethodology/Instrumentation
​Mayo Clinic Laboratories​Monday through Saturday​1 to 4 days

ASOU, CDOU, HGOU, PBOU: ​Inductively Coupled Plasma-Mass Spectrometry (ICP-MS)

CRETR:  Enzymatic Colorimetric Assay

Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)		QuantityDescriptionComments
​82175​​1​​
​82300​​1​​
​83825​​1​​
​83655​​1​​
​82570​​1​​
​82175​​1​​if needed
For most current information refer to the Marshfield Laboratory online reference manual.