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26368 Sterols, Plasma 7-Dehydrocholesterol

Sterols, Plasma 7-Dehydrocholesterol
Test Code: SLOSSO
Synonyms/Keywords

Sterols, 7-Dehydrocholesterol (Smith-Lemli-Opitz)/SLOS/RSH)

Sterols, 7-Dehydrocholesterol

SLOS and 7-dehydrocholesterol

Smith-Lemli-Opitz

Smith-Lemli-Opitz Syndrome

Sterols

Plasma (7-DHC)

Useful For

​7-dehydrocholesterol for diagnosis of Smith-Lemli-Opitz Syndrome (SLOS)

Specimen Requirements
Fasting RequiredSpecimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​NoPlasma​EDTA Lavender Top Tube (LTT)​​Lithium-heparin Green Top Tube (GTT)​3 mL​1.0 mL
Collection Processing Instructions

Ship frozen on dry ice.

Ship by overnight express carrier Monday through Thursday.

Saturday delivery may be available UPON REQUEST: Call Laboratory at (503)

494-4593 with tracking number.

Visit www.ohsu.edu Sterol Analysis Lab for requisition.

Specimen Stability Information
Specimen TypeTemperatureTime
Plasma​ ​ ​​Ambient8.5 hours​
​Refrigerated​68 hours
​Frozen​12 months
Rejection Criteria

Specimens consisting of citrate, oxalate, or fluoride plasma (blue, gray, or black topped

Tubes).

Specimen without at least two identifiers (to include patient name, DOB or MRN).​
​Specimen of less than 0.5 ml volume.
​Specimens that include broken tubes.
Specimen not refrigerated or frozen as required.
​Grossly hemolyzed specimen.
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
Oregon Health & Science University​Varies​2-4 weeks

Hexane extraction of saponified plasma lipids followed by derivatization. Gas chromatography

Reference Range Information

< 0.10 mg/dL

An interpretive report will be provided

Interpretation

​An interpretive report will be provided

Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
82542​1​Column chromatography, includes mass spectrometry, if performed, non-drug analytes not elsewhere specified, qualitative or quantitative
Synonyms/Keywords

Sterols, 7-Dehydrocholesterol (Smith-Lemli-Opitz)/SLOS/RSH)

Sterols, 7-Dehydrocholesterol

SLOS and 7-dehydrocholesterol

Smith-Lemli-Opitz

Smith-Lemli-Opitz Syndrome

Sterols

Plasma (7-DHC)

Ordering Applications
Ordering ApplicationDescription
​COM​Sterols, 7-Dehydrocholesterol
Cerner​​Sterols, 7-Dehydrocholesterol
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Fasting RequiredSpecimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)
​NoPlasma​EDTA Lavender Top Tube (LTT)​​Lithium-heparin Green Top Tube (GTT)​3 mL​1.0 mL
Collection Processing

Ship frozen on dry ice.

Ship by overnight express carrier Monday through Thursday.

Saturday delivery may be available UPON REQUEST: Call Laboratory at (503)

494-4593 with tracking number.

Visit www.ohsu.edu Sterol Analysis Lab for requisition.

Specimen Stability Information
Specimen TypeTemperatureTime
Plasma​ ​ ​​Ambient8.5 hours​
​Refrigerated​68 hours
​Frozen​12 months
Rejection Criteria

Specimens consisting of citrate, oxalate, or fluoride plasma (blue, gray, or black topped

Tubes).

Specimen without at least two identifiers (to include patient name, DOB or MRN).​
​Specimen of less than 0.5 ml volume.
​Specimens that include broken tubes.
Specimen not refrigerated or frozen as required.
​Grossly hemolyzed specimen.
Useful For

​7-dehydrocholesterol for diagnosis of Smith-Lemli-Opitz Syndrome (SLOS)

Reference Range Information

< 0.10 mg/dL

An interpretive report will be provided

Interpretation

​An interpretive report will be provided

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation
Oregon Health & Science University​Varies​2-4 weeks

Hexane extraction of saponified plasma lipids followed by derivatization. Gas chromatography

For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)
QuantityDescriptionComments
82542​1​Column chromatography, includes mass spectrometry, if performed, non-drug analytes not elsewhere specified, qualitative or quantitative
For most current information refer to the Marshfield Laboratory online reference manual.