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26493 Barbiturates Confirmation, Random, Urine (BARBU)

Barbiturates Confirmation, Random, Urine (BARBU)
Test Code: BARBUSO
Synonyms/Keywords

​Amobarbital (Amytal), Amytal (Amobarbital), Barbita (Phenobarbital), Barbiturates, Barbs, Luminal (Phenobarbital), Nembutal (Pentobarbital), Pentobarbital (Nembutal), Phenobarbital, Secobarbital (Seconal), Seconal (Secobarbital), Solfoton (Phenobarbital), Butalbital (Fiorinal)

Useful For

Detecting drug abuse involving barbiturates such as amobarbital, butalbital, pentobarbital, phenobarbital, and secobarbital

Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)		Pediatric Minimum Volume
(no repeat)
​Unpreserved Urine​Unpreserved Urine Collection container​​10 mL​5 mL​
Collection Processing Instructions

​1. Collect a random urine specimen.
2. No preservative.

Specimen Stability Information
Specimen TypeTemperatureTime
​Unpreserved Urine ​ ​​Refrigerated (preferred)​14 days
​Frozen​14 days
​Ambient ​72 hours
Interference

​No significant cautionary statements.

Performing Laboratory Information
Performing LocationDay(s) Test PerformedReport AvailableMethodology/Instrumentation
​Mayo Clinic Laboratories​Tuesday, Thursday, Sunday​3 - 5 days

Gas Chromatography-Mass Spectrometry (GC-MS) Confirmation with Quantitation

Reference Lab
Mayo Clinic Laboratories
Test Information

​Barbiturates represent a class of drugs that were originally introduced as sleep inducers. Butalbital is also used to control severe headaches. Mephobarbital and phenobarbital are frequently used to control major motor (grand mal) seizures. These drugs are commonly abused as "downers" to induce sleep after an amphetamine- or cocaine-induced "high."

Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories​

Negative

 Cutoff concentrations:

BUTALBITAL BY GC-MS

<100 ng/mL

 AMOBARBITAL BY GC-MS

<100 ng/mL

 PENTOBARBITAL BY GC-MS

<100 ng/mL

 SECOBARBITAL BY GC-MS

<100 ng/mL

 PHENOBARBITAL BY GC-MS

<100 ng/mL

Interpretation

The presence of a barbiturate in urine indicates use of one of these drugs.

Most of the barbiturates are fast acting; their presence indicates use within the past 3 days.

Phenobarbital, commonly used to control epilepsy, has a very long half-life. The presence of phenobarbital in urine indicates that the patient has used the drug sometime within the past 30 days.

Outreach CPTs
CPTModifier
(if needed)		QuantityDescriptionComments
​80345​​​​MCMA = G0480 (if appropriate)
Synonyms/Keywords

​Amobarbital (Amytal), Amytal (Amobarbital), Barbita (Phenobarbital), Barbiturates, Barbs, Luminal (Phenobarbital), Nembutal (Pentobarbital), Pentobarbital (Nembutal), Phenobarbital, Secobarbital (Seconal), Seconal (Secobarbital), Solfoton (Phenobarbital), Butalbital (Fiorinal)

Ordering Applications
Ordering ApplicationDescription
​Cerner​Barbituates Confirm (BARBU)
If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)		Pediatric Minimum Volume
(no repeat)
​Unpreserved Urine​Unpreserved Urine Collection container​​10 mL​5 mL​
Collection Processing

​1. Collect a random urine specimen.
2. No preservative.

Specimen Stability Information
Specimen TypeTemperatureTime
​Unpreserved Urine ​ ​​Refrigerated (preferred)​14 days
​Frozen​14 days
​Ambient ​72 hours
Interference

​No significant cautionary statements.

Useful For

Detecting drug abuse involving barbiturates such as amobarbital, butalbital, pentobarbital, phenobarbital, and secobarbital

Reference Range Information
Performing LocationReference Range
​Mayo Clinic Laboratories​

Negative

 Cutoff concentrations:

BUTALBITAL BY GC-MS

<100 ng/mL

 AMOBARBITAL BY GC-MS

<100 ng/mL

 PENTOBARBITAL BY GC-MS

<100 ng/mL

 SECOBARBITAL BY GC-MS

<100 ng/mL

 PHENOBARBITAL BY GC-MS

<100 ng/mL

Interpretation

The presence of a barbiturate in urine indicates use of one of these drugs.

Most of the barbiturates are fast acting; their presence indicates use within the past 3 days.

Phenobarbital, commonly used to control epilepsy, has a very long half-life. The presence of phenobarbital in urine indicates that the patient has used the drug sometime within the past 30 days.

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedReport AvailableMethodology/Instrumentation
​Mayo Clinic Laboratories​Tuesday, Thursday, Sunday​3 - 5 days

Gas Chromatography-Mass Spectrometry (GC-MS) Confirmation with Quantitation

Reference Lab
Mayo Clinic Laboratories
For billing questions, see Contacts
Outreach CPTs
CPTModifier
(if needed)		QuantityDescriptionComments
​80345​​​​MCMA = G0480 (if appropriate)
For most current information refer to the Marshfield Laboratory online reference manual.