N-terminal pro-Brain Natriuretic Peptide

Marshfield Lab Public WebSite

Marshfield Clinic Public WebSite

Test Code: NT-proBNP

Overview
Ordering
Specimen
Performing
Clinical/Interpretive
Contacts
Coding

Synonyms/Keywords

NT-proBNP

Test Components

Nt-proBNP

Useful For

This test is used as an aid in the diagnosis of congestive heart failure.

Specimen Requirements

Fasting Required	Specimen Type	Preferred Container/Tube	Acceptable Container/Tube	Specimen Volume	Specimen Minimum Volume (allows for 1 repeat)	Pediatric Minimum Volume (no repeat)
No	Plasma	Lithium-heparin Plasma Separator Tube (PST)	Sodium-heparin Green Top Tube (GTT) or EDTA Lavender Top Tube (LTT)	1.0 mL	1.0 mL	0.5 mL
No	Serum	Serum Separator Tube (SST)	Red Top Tube (RTT)	1.0 mL	1.0 mL	0.5 mL

Specimen Stability Information

Specimen Type	Temperature	Time
Serum/Plasma	Ambient	3 days
	Refrigerate	3 days
	Frozen at -20^oC	12 months

Rejection Criteria

Specimens not stored as listed above

Interference

Specimens that contain biotin at a concentraion of 250 ng/mL demonstrate a less than or equal to 10% change in results. Biotin concentrations greater than this may lead to falsely depressed results for patient samples. Results from patients taking biotin supplements or receiving high-dose biotin therapy should be interpreted with caution due to the possible interference with this test.

Performing Laboratory Information

Performing Location	Day(s) Test Performed	Analytical Time	Methodology/Instrumentation
MMC-Beaver Dam	Sunday through Saturday	2 hours	Chemiluminescent/ Siemens EXL

Reference Range Information

Performing Location	Reference Range
MMC- Beaver Dam	Patients < 75 years: 125 pg/mL Patients > or = 75 years: 450 pg/mL

Interpretation

Diagnostic Criteria:

CHF Unlikely IF:

Age <50 and NT-proBNP <450

Age 50-75 and NT-proBNP <900

Age >75 and NT-proBNP <1800

Pride CHF Score <7

CHF Very likely IF NT-proBNP >10,000 Regardless of age

NT-proBNP should be used as a rule out test for CHF.

*Biotin interference may cause inaccurate results*

Outreach CPTs

CPT	Modifier (if needed)	Quantity	Description	Comments
83880

Synonyms/Keywords

NT-proBNP

Test Components

Nt-proBNP

Ordering Applications

Ordering Application	Description
Cerner	N-terminal pro-Brain Natriuretic Peptide

If the ordering application you are looking for is not listed, contact your local laboratory for assistance.

Specimen Requirements

Fasting Required	Specimen Type	Preferred Container/Tube	Acceptable Container/Tube	Specimen Volume	Specimen Minimum Volume (allows for 1 repeat)	Pediatric Minimum Volume (no repeat)
No	Plasma	Lithium-heparin Plasma Separator Tube (PST)	Sodium-heparin Green Top Tube (GTT) or EDTA Lavender Top Tube (LTT)	1.0 mL	1.0 mL	0.5 mL
No	Serum	Serum Separator Tube (SST)	Red Top Tube (RTT)	1.0 mL	1.0 mL	0.5 mL

Specimen Stability Information

Specimen Type	Temperature	Time
Serum/Plasma	Ambient	3 days
	Refrigerate	3 days
	Frozen at -20^oC	12 months

Rejection Criteria

Specimens not stored as listed above

Interference

Useful For

This test is used as an aid in the diagnosis of congestive heart failure.

Test Components

Nt-proBNP

Reference Range Information

Performing Location	Reference Range
MMC- Beaver Dam	Patients < 75 years: 125 pg/mL Patients > or = 75 years: 450 pg/mL

Interpretation

Diagnostic Criteria:

CHF Unlikely IF:

Age <50 and NT-proBNP <450

Age 50-75 and NT-proBNP <900

Age >75 and NT-proBNP <1800

Pride CHF Score <7

CHF Very likely IF NT-proBNP >10,000 Regardless of age

NT-proBNP should be used as a rule out test for CHF.

*Biotin interference may cause inaccurate results*

For more information visit:

http://labtestsonline.org

Performing Laboratory Information

Performing Location	Day(s) Test Performed	Analytical Time	Methodology/Instrumentation
MMC-Beaver Dam	Sunday through Saturday	2 hours	Chemiluminescent/ Siemens EXL

For billing questions, see Contacts

Outreach CPTs

CPT	Modifier (if needed)	Quantity	Description	Comments
83880

Return To Top

For most current information refer to the Marshfield Laboratory online reference manual.

26534 N-terminal pro-Brain Natriuretic Peptide // <![CDATA[ _spBodyOnLoadFunctionNames.push("setupPageDescriptionCallout"); // ]]>

26534 N-terminal pro-Brain Natriuretic Peptide