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26654 Unity Screen Carrier Screen with Reflex sgNIPT

Unity Screen Carrier Screen with Reflex sgNIPT
Test Code: USCSSO
Useful For

​UNITY uses next-generation DNA sequencing and deletion analysis of HBA1, HBA2, HBB, CFTR, and SMN1 to diagnose carrier status for cystic fibrosis, spinal muscular atrophy, and hemoglobinopathies (alpha-thalassemia, beta-thalassemia, and sickle cell disease). Single nucleotide variants in the gene panel are identified by next-generation sequencing (NGS) of exons. Deletion analysis is performed by NGS and proprietary Quantitative Counting Template (QCT) technology. UNITY offers fetal risk assessment non-invasive prenatal testing (NIPT) of these single-gene disorders when a carrier is identified from pregnant, maternal blood. Single-gene NIPT is offered as an auto-reflex test that analyzes cell-free DNA (cfDNA) in blood plasma.

Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)

​Whole Blood
​3- Streck 10 mL
​N/A
​30 mL total: 10 mL in each of 3 DNA Streck tubes (30 mL total)
​20 mL
​​N/A​
Specimen Stability Information

Store and transport specimen tubes at ambient temperature (43-98 ºF or 6-37 ºC).

Specimen Type
TemperatureTime
​Whole Blood
​Ambient
​​7days
Rejection Criteria

Refrigerated or Frozen Specimens​

Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation

​BillionToOne
​Monday - Friday (samples processed Sun-Sat)
​​14 -21 days
​Next Generation Sequencing: Counting and SNP-based methodologies, QCT technology
Reference Lab
Ordering Applications
Ordering ApplicationDescription
​Cerner
Unity Screen Carrier Screen with Reflex sgNIPT​

If the ordering application you are looking for is not listed, contact your local laboratory for assistance.
Specimen Requirements
Specimen TypePreferred Container/TubeAcceptable Container/TubeSpecimen VolumeSpecimen Minimum Volume
(allows for 1 repeat)
Pediatric Minimum Volume
(no repeat)

​Whole Blood
​3- Streck 10 mL
​N/A
​30 mL total: 10 mL in each of 3 DNA Streck tubes (30 mL total)
​20 mL
​​N/A​
Specimen Stability Information

Store and transport specimen tubes at ambient temperature (43-98 ºF or 6-37 ºC).

Specimen Type
TemperatureTime
​Whole Blood
​Ambient
​​7days
Rejection Criteria

Refrigerated or Frozen Specimens​

Useful For

​UNITY uses next-generation DNA sequencing and deletion analysis of HBA1, HBA2, HBB, CFTR, and SMN1 to diagnose carrier status for cystic fibrosis, spinal muscular atrophy, and hemoglobinopathies (alpha-thalassemia, beta-thalassemia, and sickle cell disease). Single nucleotide variants in the gene panel are identified by next-generation sequencing (NGS) of exons. Deletion analysis is performed by NGS and proprietary Quantitative Counting Template (QCT) technology. UNITY offers fetal risk assessment non-invasive prenatal testing (NIPT) of these single-gene disorders when a carrier is identified from pregnant, maternal blood. Single-gene NIPT is offered as an auto-reflex test that analyzes cell-free DNA (cfDNA) in blood plasma.

For more information visit:
Performing Laboratory Information
Performing LocationDay(s) Test PerformedAnalytical TimeMethodology/Instrumentation

​BillionToOne
​Monday - Friday (samples processed Sun-Sat)
​​14 -21 days
​Next Generation Sequencing: Counting and SNP-based methodologies, QCT technology
Reference Lab
For billing questions, see Contacts
For most current information refer to the Marshfield Laboratory online reference manual.